Psychometric Evaluation of the National Institutes of Health Patient-Reported Outcomes Measurement Information System in a Multiracial, Multiethnic Systemic Lupus Erythematosus Cohort
Psychometric Evaluation of the National Institutes of Health Patient-Reported Outcomes Measurement Information System in a Multiracial, Multiethnic Systemic Lupus Erythematosus Cohort
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DOI：
10.1002/acr.23797
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发表时间：
2019-12-01
影响因子：
4.7
通讯作者：
Dall'Era, Maria
中科院分区：
文献类型：
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作者：
Katz, Patricia;Yazdany, Jinoos;Dall'Era, Maria
目的研究不同种族、不同语言的系统性红斑狼疮（SLE）患者的心理测量学表现。方法数据来自加州狼疮流行病学研究，这是一个多种族/多民族的经医生证实的SLE患者队列。大多数（n = 332）参加了面对面的研究访问，包括英语，西班牙语，广东话，或普通话进行的采访。管理了多达12份PROMIS简表（取决于语文）。另有99人仅通过电话完成了访谈。内部一致性进行了检查Cronbach的α和项目总相关。与简表36分量表和自我报告和医生评估的疾病活动的相关性评估收敛效度。所有分析均在每个人种/种族组内重复进行。在双变量分析和多元回归分析中检查了人种/种族的评分差异，控制了年龄、性别、疾病持续时间以及疾病损害和活动。结果总样本为30.0%的白色，22.3%的西班牙裔，10.9%的非洲裔美国人，33.7%的亚洲人，3.0%的其他种族/民族。77%的访谈是面对面进行的。在26.0%的西班牙裔受试者和18.6%的亚裔受试者中进行了非英语访谈。每个量表在总体上和种族/族裔群体内均表现出充分的可靠性和有效性。观察到最小的地板效应，但注意到天花板效应。除了与工作有关的项目外，大多数量表的缺失项目反应都很小。在西班牙裔和亚洲人中，按给药方式或给药语言未观察到差异。考虑到疾病状态、年龄和性别的差异后，白人和其他种族/民族之间的平均得分差异很小。结论PROMIS措施出现可靠和有效的人与狼疮的种族/民族群体。
Objective We examined psychometric performance of Patient-Reported Outcomes Measurement Information System (PROMIS) measures in a racially/ethnically and linguistically diverse cohort with systemic lupus erythematosus (SLE). Methods Data were from the California Lupus Epidemiology Study, a multiracial/multiethnic cohort of individuals with physician-confirmed SLE. The majority (n = 332) attended in-person research visits that included interviews conducted in English, Spanish, Cantonese, or Mandarin. Up to 12 PROMIS short forms were administered (depending on language availability). An additional 99 individuals completed the interview by phone only. Internal consistency was examined with Cronbach's alpha and item-total correlations. Correlations with the Short Form 36 subscales and both self-reported and physician-assessed disease activity assessed convergent validity. All analyses were repeated within each racial/ethnic group. Differences in scores by race/ethnicity were examined in bivariate analyses and by multiple regression analyses controlling for age, sex, disease duration, and disease damage and activity. Results The total sample was 30.0% white, 22.3% Hispanic, 10.9% African American, 33.7% Asian, and 3.0% other race/ethnicity. Seventy-seven percent of interviews were conducted in-person. Non-English interviews were conducted in 26.0% of the Hispanic subjects and 18.6% of the Asian subjects. Each scale demonstrated adequate reliability and validity overall and within racial/ethnic groups. Minimal floor effects were observed, but ceiling effects were noted. Missing item responses were minimal for most scales, except for items related to work. No differences were noted by mode of administration or by language of administration among Hispanics and Asians. After accounting for differences in disease status, age, and sex, few differences in mean scores between whites and other racial/ethnic groups were noted. Conclusion PROMIS measures appear reliable and valid in persons with lupus across racial/ethnic groups.