Artificial heart research and present status of clinical application in Japan
Artificial heart research and present status of clinical application in Japan
复制标题
DOI：
10.1097/01.mat.0000196711.98042.12
复制
发表时间：
2006-01-01
期刊：
影响因子：
4.2
通讯作者：
Imachi, K
中科院分区：
文献类型：
--
作者：
Imachi, K
自1959年Atsumi开始在东京大学研究人工心脏以来，日本人工心脏的研究和开发历史悠久。从那时起，东京大学的研究小组一直在开发不同类型的人工心脏，以及材料，血泵，驱动机制和控制方法。除东京大学外，日本还有12个研究所参与人工心脏的研究和开发。日本人工心脏临床应用方面，政府批准的有4台，国产2台，进口2台。在1980年至2004年期间，已经进行了697例心室辅助装置（VAD）的临床应用，包括38例18岁以下的儿科患者。近年来，经皮心肺支持的临床应用不断增加，每年有600至800例病例，包括40至60例20岁以下的患者。尽管对儿科VAD临床使用的需求不断增加，但目前在日本没有使用国产或进口器械;因此，迫切需要开发儿科VAD。
Japan has a long history of research and development of the artificial heart since Atsumi began studying artificial hearts at the University of Tokyo in 1959. Since that time, the University of Tokyo group has been developing different types of artificial hearts, as well as materials, blood pumps, driving mechanisms, and control methods. Other than the University of Tokyo, there are 12 institutes involved in artificial heart research and development in Japan. As for artificial heart clinical application in Japan, four devices were approved by the government; two are domestic, two are imported. Between 1980 and 2004, 697 cases of clinical application of a ventricular assist device (VAD) have been performed, including in 38 pediatric patients under 18 years. Recently, clinical use of percutaneous cardiopulmonary support has been increasing with 600 to 800 cases being performed every year, including in 40 to 60 patients under age 20 years. Although the requirement for clinical use of pediatric VADs is increasing, there is no device, domestic or imported, currently used in Japan; therefore, there is an urgent need for development of a pediatric VAD.