STRUCTURE OF THE HUMAN RESPIRATORY ACINUS
STRUCTURE OF THE HUMAN RESPIRATORY ACINUS
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DOI：
10.1002/aja.1001620304
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发表时间：
1981-01-01
影响因子：
--
通讯作者：
RAABE, OG
中科院分区：
文献类型：
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作者：
SCHREIDER, JP;RAABE, OG
利用人体肺末吸气状态下的硅橡胶腐蚀铸型，对几个人体肺泡标本进行了研究。在腺泡中，4例详细测量了导管的长度和直径、每根导管的肺泡数和导管的分支方式。腺泡具有不规则的分枝方式，包括二叉、三叉和侧枝。平均有8-12代导管和.apprx。7.1次。肺泡/腺泡103例。多角形肺泡的平均直径为250微米。导管的长度和直径差异很大；然而，在腺泡较近端的部分，导管的尺寸有减小的趋势。每根导管的肺泡数也不同，平均为10个肺泡数。在测量的基础上，使用代理路径模型和平均路径模型来总结数据，其中代理路径模型更适用于计算粒子在呼吸道中的沉积，平均路径模型是最能说明解剖结构的模型。
Silicone rubber corrosion casts of the human lung in a state of end-inspiration were used to study several specimens of the human pulmonary acinus. Of the acini, 4 were measured in detail with respect to duct length and diameter, the number of alveoli per duct and the branching pattern of the ducts. The acini had irregular branching patterns, including dichotomous, trichotomous and side branches. There were, on average, 8-12 duct generations and .apprx. 7.1 .times. 103 alveoli/acinus. The polygonal alveoli had an average diameter of 250 .mu.m. The lengths and diameters of the ducts varied considerably; however, the dimensions tended to decrease in the more proximal portions of the acini. The number of alveoli per duct also varied, with an average of 10 alveoli/duct. On the basis of the measurements, 2 models, a surrogate path model and an average path model, were used to summarize the data, with the surrogate path model being more useful for calculation such as particle desposition in the airways and the average path model being most illustrative of the anatomical structures.