Value of endoscopic ultrasound guided fine needle aspiration biopsy in the diagnosis of solid pancreatic masses
Value of endoscopic ultrasound guided fine needle aspiration biopsy in the diagnosis of solid pancreatic masses
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DOI：
10.1136/gut.46.2.244
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发表时间：
2000-02-01
期刊：
影响因子：
24.5
通讯作者：
Ruszniewski, P
中科院分区：
文献类型：
--
作者：
Voss, M;Hammel, P;Ruszniewski, P
目的-评估内镜超声引导下细针活检(EUS-FNAB)对胰腺实性肿块患者的可行性和诊断准确性。方法-对99名连续的胰腺肿块患者进行研究。将 EUS-FNAB 获得的组织学结果与通过手术、其他肿瘤部位活检或尸检，或结合临床病程、影像学特征和肿瘤标志物评估的最终诊断进行比较。结果-EUS-FNAB 在 90 名患者中是可行的（腺癌，n = 59；神经内分泌肿瘤，n = 15；各种肿瘤，n = 6；胰腺炎，n = 10），并在73中获得可分析材料。肿瘤大小（直径大于或等于或<25毫米）不影响获得信息丰富的活检样本的能力。诊断准确率为 74.4%（腺癌，81.4%；神经内分泌肿瘤，46.7%；其他病变，75%；p
Aim-To assess the feasibility and diagnostic accuracy of endoscopic ultrasound guided fine needle biopsy (EUS-FNAB) in patients with solid pancreatic masses.Methods-Ninety nine consecutive patients with pancreatic masses were studied. Histological findings obtained by EUS-FNAB were compared with the final diagnosis assessed by surgery, biopsy of other tumour site or at postmortem examination, or by using a combination of clinical course, imaging features, and tumour markers.Resutlts-EUS-FNAB was feasible in 90 patients (adenocarcinomas, n = 59; neuroendocrine tumours, n = 15; various neoplasms, n = 6; pancreatitis, n = 10), and analysable material was obtained in 73. Tumour size (greater than or equal to or < 25 mm in diameter) did not influence the ability to obtain informative biopsy samples. Diagnostic accuracy was 74.4% (adenocarcinomas, 81.4%; neuroendocrine tumours, 46.7%; other lesions, 75%; p