Adverse outcomes associated with personality disorder not otherwise specified in a community sample
Adverse outcomes associated with personality disorder not otherwise specified in a community sample
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DOI：
10.1176/appi.ajp.162.10.1926
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发表时间：
2005-10-01
影响因子：
17.7
通讯作者：
Brook, JS
中科院分区：
文献类型：
--
作者：
Johnson, JG;First, MB;Brook, JS
目的：作者调查了 1) 社区中被诊断患有未另行指定的人格障碍的青少年和成年人是否面临不良后果的较高风险，以及 2) 这种风险的升高是否与 DSM-IV A、B 和 C 类人格障碍相关。方法：以社区为样本，对 693 名母亲及其后代在后代的童年、青春期和成年早期进行了访谈。对后代的精神病理学、攻击行为、教育和人际困难以及自杀行为进行了评估。结果：符合 DSM-IV 人格障碍标准（未另行指定）的个体比没有人格障碍的个体更有可能在青春期和成年早期同时出现轴 I 障碍和行为、教育或人际关系问题。此外，患有其他未明确指出的人格障碍的青少年在成年早期出现教育失败、许多人际交往困难、精神障碍和严重身体攻击行为的风险显着升高。患有未另行指定的人格障碍的青少年与患有 A、B 或 C 类人格障碍或具有 I 轴障碍的青少年一样有可能出现这些不良后果。结论：一般人群中被诊断患有未另行指定的人格障碍的青少年和年轻人可能与患有 DSM-IV A、B 或 C 类人格障碍的青少年一样，患有 I 轴精神病理学，并且存在不可归因于同时发生的精神障碍的行为、教育或人际关系问题。患有未另行指定的人格障碍的个体以及患有 DSM-IV A 类、B 类或 C 类人格障碍的个体可能面临各种不良后果的显着升高的风险。
Objective: The authors investigated 1) whether adolescents and adults in the community diagnosed with personality disorder not otherwise specified are at elevated risk for adverse outcomes, and 2) whether this elevation in risk is comparable with that associated with the DSM-IV cluster A, B, and C personality disorders.Method: A community-based sample of 693 mothers and their offspring were interviewed during the offspring's childhood, adolescence, and early adulthood. Offspring psychopathology, aggressive behavior, educational and interpersonal difficulties, and suicidal behavior were assessed.Results: Individuals who met DSM-IV criteria for personality disorder not otherwise specified were significantly more likely than those without personality disorders to have concurrent axis I disorders and behavioral, educational, or interpersonal problems during adolescence and early adulthood. In addition, adolescents with personality disorder not otherwise specified were at significantly elevated risk for subsequent educational failure, numerous interpersonal difficulties, psychiatric disorders, and serious acts of physical aggression by early adulthood. Adolescents with personality disorder not otherwise specified were as likely to have these adverse outcomes as those with cluster A, B, or C personality disorders or those with axis I disorders.Conclusions: Adolescents and young adults in the general population diagnosed with personality disorder not otherwise specified may be as likely as those with DSM-IV cluster A, B, or C personality disorders to have axis I psychopathology and to have behavioral, educational, or interpersonal problems that are not attributable to co-occurring psychiatric disorders. Individuals with personality disorder not otherwise specified and individuals with DSM-IV cluster A, B, or C personality disorders are likely to be at substantially elevated risk for a wide range of adverse outcomes.