The role of chemokine receptors in the promotion of viral infections.
The role of chemokine receptors in the promotion of viral infections.
复制标题
趋化因子受体在促进病毒感染中的作用。
DOI：
10.1159/000068137
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Wang,JiMing
中科院分区：
文献类型：
--
作者：
Le,Yingying;Cui,Youhong;Ying,Guoguang;Iribarren,Pablo;Wang,JiMing
In the course of evolution, viruses that infect and replicate in animal cells have attained the capacity to utilize a variety of cell surface molecules for entry into a particular cell type. It has been reported that a large number of cell surface molecules can be exploited by viruses as receptors or coreceptors. These molecules include integrins, sialic acids, heparin sulfate and members of the immunoglobulin superfamily [1-4]. The diversity of viral receptors may reflect the capacity of the viruses to undergo rapid genetic mutation for environmental adaptation. In this regard, the human immunodeficiency virus type 1 (HIV-1) is a representative retrovirus that has evolved to recognize two distinct cellular receptors for infecting host cells: the immunoglobulin family member CD4 and one of the chemokine receptors [5]. Chemokine receptors belong to the seven-transmembrane (STM), G protein-coupled receptor superfamily and were originally shown to mediate a number of the biological activities of a group of polypeptide cytokines known as chemokines, including leukocyteThe content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products or organizations imply endorsement by the US Government. The publisher or recipient acknowledges right of the US Government to retain a nonexclusive, royalty-free license in and to any copyright covering this article. This project has been funded in whole or in part with federal funds from the National Cancer Institute, National Institutes of Health, under
DOI：
--
发表时间：
1984
期刊：
影响因子：
--
作者：
鎌田 徹
通讯作者：
鎌田 徹
7 – 动物细胞增殖的控制
影响因子：
5.4
作者：
A. Boynton;H. Leffert
通讯作者：
H. Leffert