A Prospective Study of In-utero Exposure to Magnetic Fields and the Risk of Childhood Obesity
A Prospective Study of In-utero Exposure to Magnetic Fields and the Risk of Childhood Obesity
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DOI：
10.1038/srep00540
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发表时间：
2012-07-27
影响因子：
4.6
通讯作者：
Quesenberry, Charles P., Jr.
中科院分区：
文献类型：
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作者：
Li, De-Kun;Ferber, Jeannette R.;Quesenberry, Charles P., Jr.
我们进行了一项前瞻性研究，以检查子宫内暴露于磁场（MF）是否会增加儿童肥胖的风险。参与研究的妇女在怀孕期间携带测量MF水平的仪器，并对她们的733名孩子进行了长达13年的随访，以收集有关生长模式的临床记录信息，平均每个孩子测量33次体重。产前暴露于高MF水平与后代肥胖风险增加相关（比值比= 1.69，95%置信区间：1.01-2.84）。这种关联表现出剂量-反应关系，并且在随访至研究结束的儿童中更强（风险增加2.3倍以上）。这种关联只存在于持续性肥胖中，而不存在于暂时性（不太可能）肥胖中。母亲在怀孕期间暴露于高MF可能是一个新的和以前未知的因素，有助于全球流行的儿童肥胖/超重。
We conducted a prospective study to examine whether in-utero exposure to magnetic fields (MFs) increases the risk of childhood obesity. Participating women carried a meter measuring MF levels during pregnancy and 733 of their children were followed up to 13 years to collect clinically recorded information on growth patterns with 33 weight measurements per child on average. Prenatal exposure to high MF level was associated with increased risk of being obese in offspring than those with lower MF level (odds ratio = 1.69, 95% confidence interval: 1.01-2.84). The association demonstrated a dose-response relationship and was stronger (more than 2.3 fold increased risk) among children who were followed up to the end of the study. The association existed only for persistent obesity, but not for transitory (unlikely) obesity. Maternal exposure to high MF during pregnancy may be a new and previously unknown factor contributing to the world-wide epidemic of childhood obesity/overweight.