HEAVY DRINKING AMONG NORWEGIAN MALE DRUNKEN DRIVERS - A STUDY OF GAMMA-GLUTAMYL-TRANSFERASE
HEAVY DRINKING AMONG NORWEGIAN MALE DRUNKEN DRIVERS - A STUDY OF GAMMA-GLUTAMYL-TRANSFERASE
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DOI：
10.1111/j.1530-0277.1986.tb05073.x
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发表时间：
1986-04-01
期刊：
影响因子：
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通讯作者：
MORLAND, J
中科院分区：
文献类型：
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作者：
GJERDE, H;SAKSHAUG, J;MORLAND, J
不同年龄段醉酒司机血液酒精浓度(BAC)的分布表明，29岁以上的醉酒司机中有大量对酒精的耐受性较高，其中许多人可能是酗酒者。为了解酒后驾车男性的酗酒程度，采用一种适合于溶血的新方法，对269例男性醉酒司机的血液标本进行了γ-谷氨酰胺转移酶(GGT)活性的测定。在29岁以上的醉酒司机中，有40%的人GGT活性升高，这表明这些司机中约有三分之一可能是酗酒者(每天饮酒超过80g)。在29岁以上的酒后驾车者中，BAC超过55 mmol/升(250毫克/100毫升)，63%的人GGT升高，这表明这些司机中绝大多数是酗酒者。较年轻的司机中较少有GGT活动升高。重复违法者的GGT活动表明，这一群体中酗酒者的百分比与被逮捕的醉酒司机总人口的百分比大致相同。
The distributions of blood alcohol concentrations (BACs) of different age groups of drunken drivers suggested that a large number of the drunken drivers above 29 years of age had high tolerance to alcohol, and many of these might be heavy drinkers. In order to study the extent of heavy drinking, .gamma.-glutamytransferase (GGT) activities were measured in 269 blood samples from male drunken drivers using a new method suitable for hemolyzed blood samples. Of the drunken drivers above 29 years of age, 40% and elevated GGT activities, indicating that roughly one-thrid of these drivers might be heavy drinkers (consuming more than 80g of alcohol/day). Of the drunken drivers above 29 years of age with BACs above 55 mmol/liter (250 mg/100 ml), 63% had elevated GGT, indicating that a large majority of these drivers were heavy drinkers. Fewer of the younger drivers had elevated GGT activities. The GGT activities of the repeating offenders indicated that the percentage of heavy drinkers in this group was approximately the same as in the total population of apprehended drunken drivers.