Breast tomosynthesis and digital mammography: a comparison of breast cancer visibility and BIRADS classification in a population of cancers with subtle mammographic findings
Breast tomosynthesis and digital mammography: a comparison of breast cancer visibility and BIRADS classification in a population of cancers with subtle mammographic findings
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DOI：
10.1007/s00330-008-1076-9
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发表时间：
2008-12-01
影响因子：
5.9
通讯作者：
Tingberg, Anders
中科院分区：
文献类型：
--
作者：
Andersson, Ingvar;Ikeda, Debra M.;Tingberg, Anders
主要目的是比较单视图乳腺断层合成摄影（BT）中的乳腺癌可见性与单视图或双视图数字乳腺X射线摄影（DM）中的癌症可见性。根据糖尿病乳腺癌的细微体征选择了36例患者。使用与DM图像相同的压迫角进行单视图BT，其中发现最少/不可见。在BT上，在50度的角度范围内采集了25个投影图像，剂量是单视图DM的两倍。在一项非盲共识研究中，两名乳腺成像专家对单视图和双视图DM和BT结果进行了分类，以确定癌症可见性和BIRADS癌症概率。在37个乳房中发现了40个乳腺癌。与单视图和双视图DM相比，分别有22例和11例患者的肿瘤在BT上更明显（两种比较均为p < 0.01）。单视图DM与单视图BT相比，21例患者的BIRADS分级提高（p < 0.01）。双视图DM与单视图BT相比，12例患者的BIRADS分级提高（p < 0.01）。结果表明，BT上的癌症可见性上级于DM，这表明BT可能具有更高的乳腺癌检测灵敏度。
The main purpose was to compare breast cancer visibility in one-view breast tomosynthesis (BT) to cancer visibility in one- or two-view digital mammography (DM). Thirty-six patients were selected on the basis of subtle signs of breast cancer on DM. One-view BT was performed with the same compression angle as the DM image in which the finding was least/not visible. On BT, 25 projections images were acquired over an angular range of 50 degrees, with double the dose of one-view DM. Two expert breast imagers classified one- and two-view DM, and BT findings for cancer visibility and BIRADS cancer probability in a non-blinded consensus study. Forty breast cancers were found in 37 breasts. The cancers were rated more visible on BT compared to one-view and two-view DM in 22 and 11 cases, respectively, (p < 0.01 for both comparisons). Comparing one-view DM to one-view BT, 21 patients were upgraded on BIRADS classification (p < 0.01). Comparing two-view DM to one-view BT, 12 patients were upgraded on BIRADS classification (p < 0.01). The results indicate that the cancer visibility on BT is superior to DM, which suggests that BT may have a higher sensitivity for breast cancer detection.