Comparison of in vitro effectiveness of mechanical thrombectomy devices
Comparison of in vitro effectiveness of mechanical thrombectomy devices
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DOI：
10.1016/s1051-0443(07)61678-9
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发表时间：
2001-10-01
影响因子：
2.9
通讯作者：
Heller, M
中科院分区：
文献类型：
--
作者：
Müller-Hülsbeck, S;Grimm, J;Heller, M
目的：确定以下流体动力取栓装置的体外凝块去除效果：AngioJet （AJ）、Hydrolyser （HL）、Oasis （OS）和Amplatz取栓装置（ATD）。所有设备都有6-F导管。材料与方法：5日龄猪凝块（n = 68, 8.5 g）取栓，采用无导丝AJ(gw0)，同轴0.016英寸导丝AJ(gw)；[016]，并带有0.035英寸的导丝[AJ（gw）。[035])，并在模拟股浅动脉（7毫米内径）的动脉血流模型（脉冲流量：700 L/min）中使用HL、OS和ATD。废水通过三步过滤系统（10-1,000 gm；压降：35 mm Hg）。结果：平均取栓时间为49秒（AJ(gw0)） ~ 88秒（OS; P < 0.001）。用AJ（gw）测量液体平衡。035)为0.89，而其他装置的生理盐水溶液与抽吸液的平均比例不是等容的(AJ(gw0), 0.8；AJ (gw。016), 0.78;霍奇金淋巴瘤,0.73;操作系统,0.62;P < 0.05)。剩余血栓大小从8.2 mg （AJ(gw0)）到27.3 mg (AJ（gw.035）不等；P = .079)。流体动力装置(0.6% OSI至0.98% [AJ(gw)]。[16])引起了少量的栓塞增加，分别是10mum， 100mum和1000mum。ATD（5.19%）引起最广泛的栓塞(P
PURPOSE: To determine the in vitro efficacy of clot removal of the following hydrodynamic thrombectomy devices: the AngioJet (AJ), Hydrolyser (HL), Oasis (OS), and Amplatz Thrombectomy Device (ATD). All devices have 6-F catheters.MATERIALS AND METHODS: Thrombectomy of 5-day-old porcine clots (n = 68; 8.5 g) was performed with the AJ without a guide wire [Aj(gw0)], with a coaxial 0.016-inch guide wire [AJ(gw.016)], and with a 0.035-inch guide wire [AJ(gw.035)]) and with the HL, OS, and ATD in an artery flow model (pulsed flow: 700 L/min) simulating the superficial femoral artery (7-mm inner tube diameter). The effluent was passed through a three-step filter system (10-1,000 gm; pressure drop: 35 mm Hg).RESULTS: Mean thrombectomy time ranged from 49 seconds (AJ(gw0)) to 88 seconds (OS; P < .001). The fluid balance with use of the AJ(gw.035) was 0.89, whereas the mean ratio of applied saline solution to aspirated fluid for the other devices was not isovolumetric (AJ(gw0), 0.8; AJ(gw.016), 0.78; HL, 0.73; OS, 0.62; P < .05). Remaining thrombus ranged in size from 8.2 mg (AJ(gw0)) to 27.3 mg (AJ(gw.035); P = .079). Hydrodynamic devices (0.6% OSI to 0.98% [AJ(gw.016)]) caused low amounts of added emboli greater 10 mum, 100 mum, and 1,000 mum. The ATD (5.19%) caused t4ew most extensive embolization (P