Agewise variation of vitamin B12 serum levels.
Agewise variation of vitamin B12 serum levels.
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维生素 B12 血清水平随年龄的变化。
DOI：
10.1093/geronj/11.2.142
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发表时间：
1956
期刊：
影响因子：
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通讯作者：
K. Okuda
中科院分区：
文献类型：
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作者：
B. Chow;R. Wood;A. Horonick;K. Okuda
用莱氏乳杆菌血清测定了5个机构65名19~40岁和145名58~89岁人群和114名10~70岁以上人群的维生素B12水平。随着年龄的增长，各组大鼠血清中维生素B12含量逐渐减少。当这些值按十年分组时，得到了统计上显著的回归。一项对70只大鼠进行的研究得出了类似的结果，随着年龄的增长，血清中维生素B12的含量从2周持续下降到36个月。我们调查了一些受试者的同一血液样本或同一受试者的不同样本中维生素B12的连续估计之间的差异，发现差异小于年龄造成的差异。A.M.科平。
Vitamin B12was estimated withLactobacillus leichmanniiin blood serum from 65 subjects aged from 19 to 40 and from 145 aged from 58 to 89 in 5 institutions, and from 114 randomly selected subjects aged from 10 to over 70 years. In all groups there was less vitamin B12in the serum with increasing age. When the values were grouped by decades a statistically significant regression was obtained.A study of 70 rats on stock diet gave a similar result with steady decrease in vitamin B12content of the blood serum with increase in age from 2 weeks to 36 months.Differences between successive estimations of vitamin B12in the same samples of blood from some of the human subjects, or in separate samples from the same subject, were investigated and were found to be less than the differences due to age. A. M. Copping.