A preliminary investigation of using age and distance measures in the detection of evolutionary couplings
A preliminary investigation of using age and distance measures in the detection of evolutionary couplings
复制标题
使用年龄和距离测量来检测进化耦合的初步研究
DOI：
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
Jonathan I. Maletic
中科院分区：
文献类型：
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作者：
Abdulkareem Alali;Brian Bartman;Christian D. Newman;Jonathan I. Maletic
提出了对使用两种措施提高从版本历史记录中发现的进化耦合准确性的初步研究。两种措施，即模式的年龄和模式内的项目之间的距离，与传统方法用于计算进化耦合的传统方法。目的是减少误报的数量（即对耦合的不准确或无关的主张）。提出了最初的观察结果表明，这些措施可能有可能改善计算进化耦合的结果的证据。
An initial study of using two measures to improve the accuracy of evolutionary couplings uncovered from version history is presented. Two measures, namely the age of a pattern and the distance among items within a pattern, are defined and used with the traditional methods for computing evolutionary couplings. The goal is to reduce the number of false positives (i.e., inaccurate or irrelevant claims of coupling). Initial observations are presented that lend evidence that these measures may have the potential to improve the results of computing evolutionary couplings.