Functional integration of PCR amplification and capillary electrophoresis in a microfabricated DNA analysis device
Functional integration of PCR amplification and capillary electrophoresis in a microfabricated DNA analysis device
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DOI：
10.1021/ac960718q
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发表时间：
1996-12-01
影响因子：
7.4
通讯作者：
Northrup, MA
中科院分区：
文献类型：
--
作者：
Woolley, AT;Hadley, D;Northrup, MA
微加工硅PCR反应器和玻璃毛细管电泳（CE）芯片已成功耦合，形成一个集成的DNA分析系统。该构建体结合了微型PCR装置的快速热循环能力（10摄氏度/秒加热，2.5摄氏度/秒冷却）和高速（
Microfabricated silicon PCR reactors and glass capillary electrophoresis (CE) chips have been successfully coupled to form an integrated DNA analysis system. This construct combines the rapid thermal cycling capabilities of microfabricated PCR devices (10 degrees C/s heating, 2.5 degrees C/s cooling) with the high-speed (