Depression and diabetes - A large population-based study of sociodemographic, lifestyle, and clinical factors associated with depression in type 1 and type 2 diabetes
Depression and diabetes - A large population-based study of sociodemographic, lifestyle, and clinical factors associated with depression in type 1 and type 2 diabetes
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DOI：
10.2337/diacare.28.8.1904
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发表时间：
2005-08-01
期刊：
影响因子：
16.2
通讯作者：
Dahl, AA
中科院分区：
文献类型：
--
作者：
Engum, A;Mykletun, A;Dahl, AA
目的-本研究的目的是调查与抑郁症的I型和2型糖尿病相关的因素，并测试这些因素是否与抑郁症的nondiabetic population.RESEARCH设计和方法-在一项包括60，869人，潜在的社会人口学，生活方式和临床因素的研究参与者和非糖尿病。研究了I型和2型糖尿病患者高血糖与抑郁之间的关系。抑郁水平采用医院焦虑和抑郁量表进行自评。结果：I型和2型糖尿病患者抑郁与多个因素相关。然而，这些因素与非糖尿病人群没有差异。共病慢性躯体疾病与2型糖尿病抑郁症相关，但与I型糖尿病无关。在2型糖尿病患者中，没有合并症的患者与没有慢性躯体疾病的非糖尿病人群患抑郁症的几率相同。在I型和2型糖尿病中，高血糖与抑郁症之间没有显著的相关性。结论：2型糖尿病无其他慢性躯体疾病并不增加抑郁症的风险。与I型和2型糖尿病抑郁症相关的因素与非糖尿病人群相同。
OBJECTIVE - The purpose of this study was to investigate factors associated with depression in type I and type 2 diabetes and test whether these differ from factors associated with depression in the nondiabetic population.RESEARCH DESIGN AND METHODS - in an unselected population study comprising 60,869 individuals, potential sociodemographic, lifestyle, and clinical factors were investigated in participants with and without diabetes. The associations between hyperglycemia and depression in types I and 2 diabetes were also studied. The levels of depression were self-rated by using the Hospital Anxiety and Depression Scale.RESULTS - Several factors were correlated with depression in types I and 2 diabetes. However, these factors were not different from those of the nondiabetic population. Comorbid chronic somatic diseases were associated with depression in type 2 but not type I diabetes. In type 2 diabetes, those without comorbidity had the same odds of depression as the nondiabetic population with no chronic somatic diseases. No significant associations were found for hyperglycemia in relation to depression in type I and type 2 diabetes.CONCLUSIONS - Type 2 diabetes without other chronic somatic diseases did not increase the risk of depression. Factors associated with depression in type I and type 2 diabetes were shared with the nondiabetic population.