The prevention and treatment of missing data in clinical trials.
The prevention and treatment of missing data in clinical trials.
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DOI：
10.1056/nejmsr1203730
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发表时间：
2012-10-04
期刊：
影响因子：
--
通讯作者：
Stern H
中科院分区：
文献类型：
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作者：
Little RJ;D'Agostino R;Cohen ML;Dickersin K;Emerson SS;Farrar JT;Frangakis C;Hogan JW;Molenberghs G;Murphy SA;Neaton JD;Rotnitzky A;Scharfstein D;Shih WJ;Siegel JP;Stern H
临床试验中的缺失数据可能对从试验中得出的推论的有效性产生重大影响。本文回顾了防止丢失数据的方法，如果没有，处理丢失的数据。
Missing data in clinical trials can have a major effect on the validity of the inferences that can be drawn from the trial. This article reviews methods for preventing missing data and, failing that, dealing with data that are missing.