Spontaneous hypoglycemia in diabetic patients with renal insuff- iciency.

Spontaneous hypoglycemia in diabetic patients with renal insuff- iciency.
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肾功能不全的糖尿病患者自发性低血糖。

DOI:
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发表时间:
1970
期刊:
Journal of the American Medical Association (JAMA)
影响因子:
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通讯作者:
A. Rubenstein
A. Rubenstein
中科院分区:
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文献类型:
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作者:
M. Block;A. Rubenstein

文献摘要

被引文献

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我们观察了3例糖尿病患者,其中肾功能不全与口服外源性胰岛素或降糖药的需求减少有关。所有三名患者,而被管理的饮食疗法单独,成为低血糖期间减少食物摄入量。对一名受试者的研究表明,血清胰岛素低,生长激素升高,皮质醇水平正常。肝糖原分解受损、糖异生受损或两者兼而有之可能是该综合征的原因。
We have observed three patients with diabetes mellitus, in whom renal insufficiency was associated with decreased requirements for exogenous insulin or hypoglycemic agents given orally. All three patients, while being managed on dietary therapy alone, became hypoglycemic during periods of decreased food intake. Studies on one subject demonstrated low serum insulin, elevated growth hormone, and normal cortisol levels. It seems probable that impaired hepatic glycogenolysis, glyconeogenesis, or both are responsible for this syndrome.