Heat diffusion and chemical kinetics in Mark-III FEL tissue ablation
Heat diffusion and chemical kinetics in Mark-III FEL tissue ablation
复制标题
Mark-III FEL 组织消融中的热扩散和化学动力学
DOI：
10.1117/12.461378
复制
发表时间：
2002
期刊：
影响因子：
--
通讯作者：
S. Hauger
中科院分区：
文献类型：
--
作者：
G. Edwards;M. Hutson;S. Hauger
我们提出了一些详细的理论模型，提供了一个动态帐户的实验观察到的烧蚀性能的自由电子激光调谐近6.45微米。该模型是基于热扩散和化学动力学的蛋白质和盐水的交替层的系统加热的红外马克-III自由电子激光。我们比较了3.0微米处的暴露，其中水是唯一的吸收剂，以及6.45微米处的暴露，其中蛋白质和水都吸收。马克-III超脉冲的皮秒脉冲被视为一串脉冲。我们认为发病的螺旋线圈过渡和化学键断裂的热，化学和机械性能的系统，以及激光波长和脉冲结构。
We present in some detail a theoretical model that provides a dynamical account for the experimentally observed ablative properties of an FEL tuned near 6.45 microns. The model is based on thermal diffusion and chemical kinetics in a system of alternating layers of protein and saline as heated by an infrared Mark-III FEL. We compare exposure at 3.0 microns, where water is the sole absorber, to that at 6.45 microns, where both protein and water absorb. The picosecond pulses of the Mark-III superpulse are treated as a train of impulses. We consider the onset of both the helix-coil transition and chemical bond breaking in terms of the thermal, chemical, and mechanical properties of the system as well as laser wavelength and pulse structure.