Anxiety sensitivity predicts depression severity in individuals with dissociative identity disorder.

Anxiety sensitivity predicts depression severity in individuals with dissociative identity disorder.
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DOI:
10.1016/j.jpsychires.2022.09.003
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发表时间:
2022-11
影响因子:
4.8
通讯作者:
Lebois, Lauren A. M.
Lebois, Lauren A. M.
中科院分区:
医学2区
文献类型:
--
作者:
Pan, Xi;Palermo, Cori A.;Kaplan, Chloe S.;Harnett, Nathaniel G.;Winternitz, Sherry R.;Kaufman, Milissa L.;Lebois, Lauren A. M.

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焦虑敏感涉及对焦虑相关症状的恐惧,并可加剧严重抑郁障碍和创伤后应激障碍(PTSD)症状。然而,目前尚不清楚焦虑敏感性是否在分离性认同障碍(DID)中起到类似的作用,分离性认同障碍通常是抑郁症和创伤后应激障碍共同出现的症状。我们检验了焦虑敏感度、抑郁、创伤后应激障碍与DID患者分离症状之间的关系,假设所有症状与焦虑敏感度之间存在正相关。参与者是21名寻求治疗的成年女性,她们有童年创伤史,目前患有创伤后应激障碍,确实如此。受试者完成焦虑敏感指数(ASI)、贝克抑郁问卷-II、童年创伤问卷、多维度分离问卷和创伤后应激障碍量表(DSM-5)。ASI包括评估认知、身体和社交领域焦虑敏感度的子量表。参与者报告说,他们对焦虑高度敏感。多元回归分析表明,ASI认知分量表是抑郁症状的最强预测因子。焦虑敏感度和创伤后应激障碍或分离症状之间没有直接的联系。我们进行了中介分析,检验了认知焦虑敏感性与分离症状之间的间接关系,发现抑郁症状对认知焦虑敏感性有显著的间接影响。我们的结果表明,认知焦虑敏感性或对认知障碍的恐惧与DID的症状严重程度有关。这些发现强调了评估和利用针对焦虑敏感性的干预措施的必要性,这反过来可能会缓解DID患者的抑郁和分离症状。
Anxiety sensitivity involves the fear of anxiety-related symptoms and can exacerbate both major depressive disorder and posttraumatic stress disorder (PTSD) symptoms. However, it is unclear if anxiety sensitivity plays a similar role in dissociative identity disorder (DID) where symptoms of depression and PTSD commonly co-occur. We examined the association between anxiety sensitivity, depression, PTSD and dissociative symptoms in DID, hypothesizing a positive association between all symptoms and anxiety sensitivity. Participants were 21 treatment-seeking adult females with histories of childhood trauma, current PTSD, and DID. Participants completed the Anxiety Sensitivity Index (ASI), Beck Depression Inventory-II, Childhood Trauma Questionnaire, Multidimensional Inventory of Dissociation, and PTSD Checklist for DSM-5. The ASI included subscales that assessed anxiety sensitivity in cognitive, physical, and social domains. Participants reported high levels of anxiety sensitivity. A multiple regression analysis demonstrated that the ASI cognitive subscale was the strongest predictor of depressive symptoms. No direct associations were identified between anxiety sensitivity and PTSD or dissociative symptoms. We conducted a mediation analysis to test an indirect relationship between cognitive anxiety sensitivity and dissociative symptoms, and found a significant indirect effect through depressive symptoms. Our results suggest that cognitive anxiety sensitivity or the fear of cognitive dyscontrol is linked with symptom severity in DID. These findings emphasize the need to assess for and utilize interventions that target anxiety sensitivity, which may in turn alleviate symptoms of depression and dissociation in DID.
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