Reviving Protein-Observed 19F Lineshape Analysis for Deep Insight into Protein-Ligand Binding Events
Reviving Protein-Observed 19F Lineshape Analysis for Deep Insight into Protein-Ligand Binding Events
复制标题
恢复蛋白质观察的 19F 线形分析，以深入了解蛋白质-配体结合事件
DOI：
10.1016/j.bpj.2020.04.003
复制
发表时间：
2020
影响因子：
3.4
通讯作者：
Showalter, Scott A.
中科院分区：
文献类型：
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作者：
Showalter, Scott A.
当我还是圣路易斯华盛顿大学的一名研究生时，卡尔·弗里登教授交付了据我所知第一个用于19 F探测的低温冷却核磁共振探针。该探针被用于研究大肠杆菌周质蛋白PapD的折叠动力学，
When I was a graduate student at Washington University in St. Louis, Professor Carl Frieden took delivery of what was, to my knowledge, the first cryogenically cooled NMR probe for 19 F-detection. This probe was put to brilliant use investigating the folding kinetics of the Escherichia coli periplasmic protein PapD (