Yolk-shell type nanoprobe with excellent fluorescence 'blinking' behavior for optical super resolution imaging
Yolk-shell type nanoprobe with excellent fluorescence 'blinking' behavior for optical super resolution imaging
复制标题
蛋黄壳型纳米探针具有出色的荧光“闪烁”行为，适用于光学超分辨率成像
DOI：
10.1088/1361-6528/aa7536
复制
发表时间：
2017
期刊：
影响因子：
3.5
通讯作者：
崔一平
中科院分区：
文献类型：
--
作者：
陆驹;宗慎飞;王著元;陈晨;张益之;崔一平
介绍了一种用于超分辨率成像的新型蛋黄壳型纳米探针。利用所提出的纳米探针和基于单分子定位的超分辨率成像策略，实现了细胞内纳米颗粒的跟踪和超分辨率成像。该探针的定位精度约为50 nm，单分子定位显微镜只需要一个单一的激发激光器，不需要特定的成像缓冲。
A new yolk-shell type nanoprobe for super-resolution imaging is demonstrated. Using the proposed nanoprobe and single molecule localization based super resolution imaging strategy, intracellular nanoparticle tracking and super-resolution imaging are realized. The localization precision is about 50 nm and single-molecule localization microscopy using the proposed nanoprobe requires only one single excitation laser and no specific imaging buffer.