Urinary mercury in people living near point sources of mercury emissions
Urinary mercury in people living near point sources of mercury emissions
复制标题
DOI：
10.1016/j.scitotenv.2005.08.048
复制
发表时间：
2006-09-01
影响因子：
9.8
通讯作者：
Eugensson, Marie Haeger
中科院分区：
文献类型：
--
作者：
Barregard, Lars;Horvat, Milena;Eugensson, Marie Haeger
作为欧洲氯碱工厂汞排放 (EMECAP) 项目的一部分，我们测试了这样的假设：使用汞电池的氯碱工厂周围的环境空气受到汞污染，会增加工厂附近居民的内部汞剂量。对居住在瑞典或意大利氯碱工厂附近的 225 名个人以及来自两个参考地区的 256 名年龄和性别匹配的个人进行了尿液中汞 (U-Hg) 的测定。对可能影响汞暴露的其他因素进行了检查。对工厂周围总气态汞 (TGM) 的排放和浓度进行了测量和建模。在工厂附近居住的人群中，未发现 U-Hg 增加。当比较仅限于没有牙科汞合金和低鱼类消费的受试者时，情况也是如此。空气中汞的排放量是背景水平的两倍，但对居住区长期平均排放量仅贡献约2 ng/m(3)。在意大利，使用牙科汞合金的受试者的 U-Hg 中位水平为 1.2 μg/g 肌酸酐 (μ g/gC)，在瑞典为 0.6 μg/gC。在没有使用牙科汞合金的个体中，中位数分别为 0.9 μg/gC 和 0.2 μg/gC。汞合金填充物的数量以及咀嚼、鱼类消费和女性与较高的 U-Hg 相关。各国之间的差异可能是由于意大利的鱼类消费量较高，部分去甲基甲基汞 (MeHg) 通过尿液排出。事后功效计算表明，如果背景汞暴露量较低，则可能会证明 U-Hg 的增加仅约 10 ng/m(3)，作为点源对环境汞的贡献。 (c) 2005 Elsevier B.V 保留所有权利。
As part of the European Mercury Emissions from Chlor Alkali Plants (EMECAP) project we tested the hypothesis that contamination of ambient air with mercury around chlor alkali plants using mercury cells would increase the internal dose of mercury in people living close to the plants. Mercury in urine (U-Hg) was determined in 225 individuals living near a Swedish or an Italian chlor alkali plant, and in 256 age- and sex-matched individuals from two reference areas. Other factors possibly affecting mercury exposure were examined. Emissions and concentrations of total gaseous mercury (TGM) around the plants were measured and modeled.No increase in U-Hg could be demonstrated in the populations living close to the plants. This was the case also when the comparison was restricted to subjects with no dental amalgam and low fish consumption. The emissions of mercury to air doubled the background level, but contributed only about 2 ng/m(3) to long-term averages in the residential areas. The median U-Hg levels in subjects with dental amalgam were 1.2 mu g/g creatinine (mu g/gC) in Italy and 0.6 mu g/gC in Sweden. In individuals without dental amalgam, the medians were 0.9 mu g/gC and 0.2 mu g/gC, respectively. The number of amalgam fillings, as well as chewing, fish consumption, and female sex were associated with higher U-Hg. The difference between the countries is probably due to higher fish consumption in Italy, demethylated methyl mercury (MeHg) being partly excreted in urine.Post hoc power calculations showed that if the background mercury exposure is low it may be possible to demonstrate an increase in U-Hg of as little as about 10 ng/m(3) as a contribution to ambient mercury from a point source. (c) 2005 Elsevier B.V All rights reserved.