Genetic control of sex determination in the germ line of Caenorhabditis elegans.
Genetic control of sex determination in the germ line of Caenorhabditis elegans.
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秀丽隐杆线虫种系性别决定的遗传控制。
DOI：
10.1098/rstb.1988.0110
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Kimble,J
中科院分区：
文献类型：
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作者：
Kimble,J
秀丽隐杆线虫通常以两种性别之一的形式存在：自我受精的雌雄同体或雄性。雌雄同体或雄性的发育需要每个组织以性别特异性的方式分化。在这篇综述中，我讨论了遗传控制的性别决定在单一组织的癌。秀丽隐杆线虫：生殖系。生殖系的性别决定取决于两种基因的作用：一种基因在所有组织中起全局作用，指导男性或女性的发育；另一种基因仅在生殖系中起作用，指定精子发生或卵子发生。首先，我考虑一个组织特异性的性别决定基因，fog-1，它促进生殖系中的精子发生。其次，我考虑了生殖系配子发生的雌雄同体模式的调节，首先产生精子，然后产生卵母细胞。
The nematodeCaenorhabditis elegansnormally exists as one of two sexes: self-fertilizing hermaphrodite or male. Development as hermaphrodite or male requires the differentiation of each tissue in a sex-specific way. In this review, I discuss the genetic control of sex determination in a single tissue ofC. elegans: the germ line. Sex determination in the germ line depends on the action of two types of genes: - those that act globally in all tissues to direct male or female development and those that act only in the germ line to specify either spermatogenesis or oogenesis. First, I consider a tissue-specific sex-determining gene,fog-1, which promotes spermatogenesis in the germ line. Second, I consider the regulation of the hermaphrodite pattern of germ line gametogenesis where first sperm and then oocytes are produced.