Molecular detection and characterization of tick-borne hemoparasites and Anaplasmataceae in dogs in major cities of Malawi
Molecular detection and characterization of tick-borne hemoparasites and Anaplasmataceae in dogs in major cities of Malawi
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DOI：
10.1007/s00436-020-06967-y
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发表时间：
2020-11-22
影响因子：
2
通讯作者：
Nakao, Ryo
中科院分区：
文献类型：
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作者：
Chatanga, Elisha;Kainga, Henson;Nakao, Ryo
在过去的十年里，狗中的壁虱传播病原体(TBP)引起了人们的极大关注，因为现在已知有些是人畜共患病，对动物和人类健康部门都构成了威胁。尽管全世界关于犬类Tbps的研究数量有所增加，但只有少数研究是在资源有限的国家进行的，这些国家的研究优先考虑食用动物，而不是同伴动物。本研究通过分子生物学技术，对马拉维三个主要城市的209只家养和流浪狗进行了巴贝斯虫属、肝孢子属、无浆体属和埃利希菌属的结核杆菌感染情况调查。在接受检查的犬中，93只(44.5%)至少感染了一种TBP。检出罗氏巴贝斯虫23.1%，沃氏巴贝斯虫2.9%，犬肝精子19.1%，无浆体2.4%，犬埃立克体3.8%。这是第一项提供证据证明马拉维的狗感染了Tbps的分子研究。由于检测到的病原体影响动物的健康，因此需要对兽医、训犬员和宠物主人进行敏化。需要对获得兽医护理的有限或没有机会的农村地区进行进一步研究，以确定TBP在狗身上的感染程度。
Tick-borne pathogens (TBPs) in dogs have attracted much attention over the last decade since some are now known to be zoonotic and pose a threat to both animal and human health sectors. Despite the increase in the number of studies on canine TBPs worldwide, only a few studies have been conducted in resource-limited countries where research priority is given to food animals than companion animals. In the present study, the occurrence of TBPs of the genera Babesia, Hepatozoon, Anaplasma, and Ehrlichia was investigated in 209 owned and stray dogs in three major cities in Malawi through molecular techniques. Among the examined dogs, 93 (44.5%) were infected with at least one TBP. The detection rates were 23.1% for Babesia rossi, 2.9% for B. vogeli, 19.1% for Hepatozoon canis, 2.4% for Anaplasma platys, and 3.8% for Ehrlichia canis. This is the first molecular study that has provided evidence that dogs in Malawi are infected with TBPs. Sensitization is required for veterinary practitioners, dog handlers, and pet owners as the detected pathogens affect the animals' wellbeing. Further studies focusing on rural areas with limited or no access to veterinary care are required to ascertain the extent of the TBP infection in dogs.