Management of heat in laser tissue welding using NIR cover window material.
Management of heat in laser tissue welding using NIR cover window material.
复制标题
使用 NIR 盖窗材料进行激光组织焊接中的热量管理。
DOI：
10.1002/lsm.21143
复制
发表时间：
2011
影响因子：
2.4
通讯作者：
Alfano,RobertR
中科院分区：
文献类型：
--
作者：
Sriramoju,Vidyasagar;Savage,Howard;Katz,Alvin;Muthukattil,Ronex;Alfano,RobertR
激光组织焊接（Lasertissuewelding，LTW）是一种利用激光辐射诱导生物组织融合的外科伤口闭合新方法。与LTW相关的分子动力学是热和非热mechanism.ObjectivesThis研究专门集中在更好的热管理，以减少热损伤的组织在LTW使用近红外激光辐射.MethodsAn红外连续波（CW）激光辐射在1，使用对应于来自水的组合振动模式的吸收带的450 nm波长将离体猪主动脉焊接在一起。在这些研究中，我们测量了最佳的激光功率和扫描速度，以获得更好的焊缝抗拉强度和更少的组织脱水。从焊接的组织中大量的水分损失导致细胞死亡和组织屈曲。各种导热光学盖窗口被用作散热器，以减少热效应在LTW期间的热量耗散。该方法的最佳使用可防止组织屈曲并最大限度地减少水分流失。金刚石、蓝宝石、BK 7、熔融石英和红外石英透明光学盖windows.ConclusionsThe数据从这项研究表明，红外石英作为材料具有最佳的导热性是理想的激光焊接猪主动脉。激光外科医学43：991-997，2011年。© 2011 Wiley Periodicals，Inc.
BackgroundLaser tissue welding (LTW) is a novel method of surgical wound closure by the use of laser radiation to induce fusion of the biological tissues. Molecular dynamics associated with LTW is a result of thermal and non‐thermal mechanisms.ObjectivesThis research focuses exclusively on better heat management to reduce thermal damage of tissues in LTW using a near infrared laser radiation.MethodsAn infrared continuous‐wave (CW) laser radiation at 1,450 nm wavelength corresponding to the absorption band from combination vibrational modes of water is used to weld together ex vivo porcine aorta.ResultsIn these studies we measured the optimal laser power and scan speed, for better tensile strength of the weld and lesser tissue dehydration. Significant amount of water loss from the welded tissue results in cellular death and tissue buckling. Various thermally conductive optical cover windows were used as heat sinks to reduce thermal effects during LTW for the dissipation of the heat. The optimal use of the method prevents tissue buckling and minimizes the water loss. Diamond, sapphire, BK7, fused silica, and IR quartz transparent optical cover windows were tested.ConclusionsThe data from this study suggests that IR‐quartz as the material with optimal thermal conductivity is ideal for laser welding of the porcine aorta. Lasers Surg. Med. 43:991–997, 2011. © 2011 Wiley Periodicals, Inc.