Localization of human somatosensory cortex using spatially filtered magnetoencephalography
Localization of human somatosensory cortex using spatially filtered magnetoencephalography
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DOI：
10.1016/s0304-3940(03)00108-3
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发表时间：
2003-04-17
影响因子：
2.5
通讯作者：
Cheyne, DO
中科院分区：
文献类型：
--
作者：
Gaetz, WC;Cheyne, DO
基于最小方差波束形成（合成孔径磁测法（SAM））的空间滤波算法应用于单次试验神经磁记录，以定位初级体感皮层。采用全脑磁图系统记录电刺激左右正中神经的脑磁图（MEG）反应，并采用SAM空间滤波和偶极子分析进行定位。空间滤波A，应用于单次试验神经磁记录，以在15-300 Hz范围内产生活动状态（0-50 ms）和控制状态（~ 50 - 0 ins）之间的源功率的三维差异图像。在SAM图像中，N20 m偶极子位置与功率最大增加位置之间的平均差异为3.7 mm（1.5 mm SD），并定位于初级体感皮层。对SAM峰值位置的空间滤波输出的时间-频率分析显示，与N20 m响应一致的60-100 Hz频带的短暂（10 ms）增加和较长的持续时间（约10 ms）。80 ms）的增加，在10-40 Hz频带的功率后，N20米开始。这些结果表明，基于波束形成器的空间滤波方法，如SAM，可用于定位由正中神经刺激产生的时间离散皮层活动。(C)2003爱思唯尔科学爱尔兰有限公司保留所有权利。
A spatial filter algorithm based on minimum-variance beamforming (synthetic aperture magnetometry (SAM)) was applied to single trial neuromagnetic recordings in order to localize primary somatosensory cortex. Magnetoencephalography (MEG) responses to electrical stimulation of the right and left median nerve were recorded using a,,whole-head MEG system and localized using both SAM spatial filtering and dipole analysis. Spatial filtering A,as applied to single trial neuromagnetic recordings to produce 3-dimensional difference images of source power between active (0-50 ms) and control states (-50-0 ins) in the range of 15-300 Hz. Average difference between N20m dipole location and location of maximal increase in power in the SAM images was 3.7 mm (1.5 mm SD) and localized to primary somatosensory cortex. Time-frequency analysis of spatially filtered output for the peak SAM locations showed a brief ( 10 ms) increase in the 60-100 Hz band coincident with the N20m response and a longer duration (approx. 80 ms) increase in power in the 10-40 Hz band following N20m onset. These results indicate that beamformer based spatial filter methods such as SAM can be used to localize temporally discrete cortical activity produced by median nerve stimulation. (C) 2003 Elsevier Science Ireland Ltd. All rights reserNed.