Magnesium as a biodegradable and bioabsorbable material for medical implants
Magnesium as a biodegradable and bioabsorbable material for medical implants
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DOI：
10.1007/s11837-009-0129-0
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发表时间：
2009-09-01
期刊：
影响因子：
2.6
通讯作者：
Manuel, Michele V.
中科院分区：
文献类型：
--
作者：
Brar, Harpreet S.;Platt, Manu O.;Manuel, Michele V.
多年来，不锈钢、钴铬合金和钛合金一直是用于承重应用的主要生物材料。然而，随着对临时植入物应用中的结构材料的需求的增长，正在寻求提供短期结构支撑并且可以在愈合后被重新吸收到体内的材料。由于传统金属生物材料通常具有生物相容性但不可生物降解，因此镁基合金在生物医学应用中的潜力引起了更多关注。本文综述了镁作为生物可吸收植入材料的历史和现状。还讨论了镁-锌-钙合金，表现出有前途的降解行为的发展。
For many years, stainless steel, cobalt-chromium, and titanium alloys have been the primary biomaterials used for load-bearing applications. However, as the need for structural materials in temporary implant applications has grown, materials that provide short-term structural support and can be reabsorbed into the body after healing are being sought. Since traditional metallic biomaterials are typically biocompatible but not biodegradable, the potential for magnesium-based alloys in biomedical applications has gained more interest. This paper summarizes the history and current status of magnesium as a bioabsorbable implant material. Also discussed is the development of a magnesium-zinc-calcium alloy that demonstrates promising degradation behavior.