A Microfabricated Rotary Pump
A Microfabricated Rotary Pump
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DOI：
10.1023/a:1012412916446
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发表时间：
2001-12-01
影响因子：
2.8
通讯作者：
Quake, Stephen R.
中科院分区：
文献类型：
--
作者：
Chou, Hou-Pu;Unger, Marc A.;Quake, Stephen R.
因为微流体装置在低雷诺数下操作，所以许多流体操作受到扩散的限制。我们已经开发了一种微型旋转泵，并证明了主动混合可以用来克服在两个应用程序中的缓慢扩散过程。首先，我们表明，试剂的混合可以有效地完成广泛的扩散常数的对象。第二，我们展示了如何将表面结合测定的反应动力学增强近两个数量级。
Because microfluidic devices operate at low Reynolds number, many fluidic operations are limited by diffusion. We have developed a microfabricated rotary pump and demonstrated that active mixing can be used to overcome the slow diffusion process in two applications. First, we showed that mixing of reagents could be efficiently accomplished for objects of a wide range of diffusion constants. Second, we showed how reaction kinetics of a surface-binding assay can be enhanced by nearly two orders of magnitude.