Convolutional Neural Networks for Classifying Chromatin Morphology in Live-Cell Imaging.
Convolutional Neural Networks for Classifying Chromatin Morphology in Live-Cell Imaging.
复制标题
用于活细胞成像中染色质形态分类的卷积神经网络。
DOI:
10.1007/978-1-0716-2221-6_3
复制
发表时间:
2022
期刊:
影响因子:
--
通讯作者:
Ulicna K
中科院分区:
文献类型:
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作者:
Ulicna K
Chromatin is highly structured, and changes in its organization are essential in many cellular processes, including cell division. Recently, advances in machine learning have enabled researchers to automatically classify chromatin morphology in fluorescence microscopy images. In this protocol, we develop user-friendly tools to perform this task. We provide an open-source annotation tool, and a cloud-based computational framework to train and utilize a convolutional neural network to automatically classify chromatin morphology. Using cloud compute enables users without significant resources or computational experience to use a machine learning approach to analyze their own microscopy data.