The culture of experimentation in epidemiology-50 years later.
The culture of experimentation in epidemiology-50 years later.
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流行病学实验文化——50 年后。
DOI：
10.1093/ije/dyac181
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发表时间：
2022
影响因子：
7.7
通讯作者：
Branas,CharlesC
中科院分区：
文献类型：
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作者：
Branas,CharlesC
国际流行病学杂志，2022 年，1705–1710 https://doi。 org/10.1093/ije/dyac181 提前获取发布日期：2022 年 9 月 15 日编辑研究。 9 那么，在流行病学领域继续使用随机对照试验和一般试验发生了什么？我问这个问题并没有假设 RCT 是某种黄金标准——这一说法已经受到适当的质疑一段时间了。 2 然而，我确实是从将随机对照试验和试验视为另一种类型的研究设计的角度提出这个问题的，它们对健康促进和疾病预防有其独特和有价值的贡献。如果与其他独特且有价值的研究设计（例如队列研究或病例对照研究）并肩考虑，我们可以而且也许应该假设，在过去的半个世纪里，流行病学领域在应用这些不同的研究设计方面已经形成了某种程度的平等。如果我们考虑流行病学最古老和引用最多的期刊之一《IJE》的出版活动，这种平等似乎并非如此。 PubMed 对所有 IJE 出版物进行的 50 年回顾证实了这一点。为了证明这一说法背后的一些数字，我通过 PubMed 搜索访问并下载了数据。 gov，由美国国立卫生研究院/国家医学图书馆的国家生物技术信息中心主办。 10 在限制到 1972 年至 2021 年之后，提交了以下搜索字符串：(i)(“International Journal of Epidemiology”[期刊])；(ii)(“International Journal of Epidemiology”[期刊]) AND 试验[标题/摘要]；(iii)(“International Journal of Epidemiology”[期刊]) AND 队列[标题/摘要]； (iv)（《国际流行病学杂志》[期刊]）和病例对照[标题/摘要]。这些检索有效地确定了 1972 年至 2021 年所有 IJE 出版物的标题或摘要中提到的术语“试验”、“队列”和“病例对照”。2022 年被省略，因为在分析时它不完整。文章包括经过同行评审的原创研究提交以及其他文章类型，例如评论和社论。
International Journal of Epidemiology, 2022, 1705–1710 https://doi. org/10.1093/ije/dyac181 Advance Access Publication Date: 15 September 2022 Editorial studies. 9 So what then has occurred as to the continued use of RCTs, and trials in general, for the field of epidemiology? I ask this with no assumption that the RCT is some sort of gold standard—that claim has been appropriately questioned for some time. 2 However, I do ask the question from the perspective of considering RCTs and trials as just another type of study design, with their own unique and valuable contributions to health promotion and disease prevention. If considered shoulder-to-shoulder with other unique and valuable study designs, such as cohort or casecontrol studies, we could, and perhaps should, assume that some level of parity in terms of the application of these various study designs has evolved over the past half-century in epidemiology.This parity does not seem to be the case if we consider the publication activity of one of epidemiology’s oldest and most cited journals, the IJE. A 50-year PubMed review of all IJE publications bears this out. To put some numbers behind this claim, I visited and downloaded data via searches on PubMed. gov, which is hosted by the National Institutes of Health/National Library of Medicine’s National Center for Biotechnology Information. 10 After restricting to years 1972 to 2021, the following searches strings were submitted:(i)(‘International Journal of Epidemiology’[Journal]);(ii)(‘International Journal of Epidemiology’[Journal]) AND trial [Title/Abstract];(iii)(‘International Journal of Epidemiology’[Journal]) AND cohort [Title/Abstract]; and (iv)(‘International Journal of Epidemiology’[Journal]) AND case-control [Title/Abstract]. These searches effectively ascertained mention of the terms ‘trial’,‘cohort’and ‘case-control’in the titles or abstracts of all IJE publications from 1972 to 2021. The year 2022 was omitted as it was incomplete at the time of this analysis. Articles included peer-reviewed submissions of original research as well as other article types such as reviews and editorials.