Psychiatric disorders among bariatric surgery candidates: relationship to obesity and functional health status.
Psychiatric disorders among bariatric surgery candidates: relationship to obesity and functional health status.
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DOI：
10.1176/ajp.2007.164.2.328
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发表时间：
2007-02
期刊：
影响因子：
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通讯作者：
M. Kalarchian;M. Marcus;M. Levine;A. Courcoulas;P. Pilkonis;Rebecca M Ringham;Julia N. Soulakova;L. Weissfeld;Dana L. Rofey
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文献类型：
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作者：
M. Kalarchian;M. Marcus;M. Levine;A. Courcoulas;P. Pilkonis;Rebecca M Ringham;Julia N. Soulakova;L. Weissfeld;Dana L. Rofey
目的本研究旨在记录减肥手术候选者的精神疾病，并探讨精神病理与肥胖程度和功能健康状况的关系。方法收集288例手术患者的人口学和临床资料。评估独立于术前筛选和批准过程进行。研究组以女性（83.3%）和白人（88.2%）为主。平均体重指数（BMI）为52.2 kg/m(2) (SD=9.7)，平均年龄为46.2岁（SD=9.4）。结果：约66%的参与者有至少一种I轴障碍的终生病史，38%的参与者在术前评估时符合诊断标准。此外，29%的患者符合一种或多种II轴疾病的标准。轴I精神病理与BMI呈正相关，轴I和轴II精神病理与医学结果研究36项简短健康调查得分较低相关。结论：目前和过去的DSM-IV精神疾病在减肥手术患者中普遍存在，并且与肥胖程度较高和功能健康状态较低相关，这突出了了解手术准备和结果的潜在影响的必要性。未来的工作也将集中在手术后精神障碍的过程及其与体重减轻和维持的关系。
OBJECTIVE The present study was designed to document psychiatric disorders among candidates for weight loss surgery and to examine the relationship of psychopathology to degree of obesity and functional health status. METHOD The authors collected demographic and clinical information from 288 individuals seeking surgery. Assessments were administered independently of the preoperative screening and approval process. The study group was mostly female (83.3%) and white (88.2%). Mean body mass index (BMI) of the group was 52.2 kg/m(2) (SD=9.7), and the mean age was 46.2 years (SD=9.4). RESULTS Approximately 66% of the participants had a lifetime history of at least one axis I disorder, and 38% met diagnostic criteria at the time of preoperative evaluation. In addition, 29% met criteria for one or more axis II disorders. Axis I psychopathology, but not axis II, was positively related to BMI, and both axis I and axis II psychopathology were associated with lower scores on the Medical Outcomes Study 36-item Short-Form Health Survey. CONCLUSIONS Current and past DSM-IV psychiatric disorders are prevalent among bariatric surgery candidates and are associated with greater obesity and lower functional health status, highlighting the need to understand potential implications for surgery preparation and outcome. Future work also will focus on the course of psychiatric disorder during the post-surgery period and its relationship to weight loss and maintenance.