Potential side effects of dental amalgam restorations. (I). An oral and medical investigation.
Potential side effects of dental amalgam restorations. (I). An oral and medical investigation.
复制标题
牙科汞合金修复的潜在副作用。
DOI：
10.1111/j.1600-0722.1997.tb00206.x
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发表时间：
1997
影响因子：
1.9
通讯作者：
Jan
中科院分区：
文献类型：
--
作者：
John Bratel;Torgny Haraldson;B. Meding;Evtim Yontchev;S. Öhman;Jan
本研究的目的是探讨健康状况和自我报告的不良反应与牙科汞合金充填之间的可能联系。一组连续的50名患者（索引组），涉及投诉自我相关的牙科汞合金充填，与对照组的年龄，性别和邮政编码相匹配的个人进行了比较。患者接受了口腔，口颌，医学和临床化学检查。检测了血液、尿液和头发中的汞含量。结果显示，指数组中躯体疾病更常见（38%对6%）。指标组74%的患者报告了与颅下颌功能障碍相关的症状，对照组为24%，诊断率分别为62%和36%。两组的口腔健康状况和汞合金表面数量相似。在任何一组中均未发现汞皮肤斑贴试验阳性。来自鱼类消费、职业接触以及血液和尿液中的汞含量的估计汞摄入量也相似，远低于预期会对健康产生负面影响的水平。汞合金表面数量与血浆和尿液中汞含量之间的相关性（r=0.43）表明，两组患者的牙科汞合金治疗均释放汞。由于指标患者和对照组的汞水平相似，汞不是患者报告的健康受损的可能原因。
The aim of this study was to explore a possible association between health status and self-reported adverse effects related to dental amalgam restorations. A group of 50 consecutive patients (index group), referred for complaints self-related to dental amalgam restorations, was compared with a control group of individuals matched by age, sex and postal zip code. The patients underwent an oral, stomatognathic, medical and clinical chemistry examination. Mercury levels were examined in blood, urine and hair. The results revealed that somatic diseases were more common in the index group (38% versus 6%). Symptoms related to cranio-mandibular dysfunction were reported by 74% of the patients in the index group versus 24% in the control group, and were diagnosed in 62% and 36%, respectively. The oral health status and the number of amalgam surfaces were similar in the 2 groups. No positive skin patch test to mercury was found in any of the groups. The estimated mercury intake from fish consumption, occupational exposure, and mercury levels in blood and urine were also similar and far below levels, where negative health effects would be expected. The correlation between the number of amalgam surfaces and mercury levels in plasma and urine (r=0.43) indicated a release of mercury from dental amalgam restorations in both groups. Since the mercury levels were similar among index patients and controls, mercury was not a likely cause of the impaired health reported by the patients.