Propranolol and response bias: an extension of findings reported by Corwin et al.

Propranolol and response bias: an extension of findings reported by Corwin et al.
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普萘洛尔和反应偏差:Corwin 等人报告的研究结果的延伸。

DOI:
10.1016/0006-3223(91)90021-d
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发表时间:
1991
影响因子:
10.6
通讯作者:
Hauck,WW
Hauck,WW
中科院分区:
医学1区
文献类型:
--
作者:
Callaway,E;Halliday,R;Perez-Stable,EJ;Coates,TJ;Hauck,WW

文献摘要

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J. Corwin等人对高血压患者的一项大型研究数据进行了分析,以检验心得安对决策中的保守偏见的影响的普遍性(见PA, Vol 77: 26278;例如,当数字识别不确定时,Ss倾向于说不)。312名18-59岁轻度舒张压高血压患者每天服用5片80毫克药片(心得安或安慰剂),并在服药前、服药3个月和1年后进行一系列检查。在一项识别测试中,3个月时服用80毫克以上心得安的婴儿倾向于变得更加谨慎;这些变化在12个月时未见。在连续的性能测试中,服用心得安的Ss在3个月和12个月时的平均反应时间(RT)均显着减慢(PsycINFO Database Record (c) 2018 APA,所有权利保留)。
Analyzed data from a large study of hypertensive patients to examine the generality of propranolol's effect on a conservative bias in decision making found by J. Corwin et al (see PA, Vol 77: 26278; eg, Ss tend to say no when uncertain in number recognition). 312 18–59 yr old mild diastolic blood pressure hypertensives received up to 5 80 mg tablets/day (propranolol or placebo) and were given a battery of tests before medication and after 3 mo and 1 yr on medication. On a recognition test, Ss receiving more than 80 mg propranolol at 3 mo tended to become more cautious; these changes were not seen at 12 mo. On a continuous performance test, Ss receiving propranolol had significant slowing of mean reaction time (RT) at both 3 and 12 mo.(PsycINFO Database Record (c) 2018 APA, all rights reserved)