The Genus Phyllanthus: An Ethnopharmacological, Phytochemical, and Pharmacological Review.

The Genus Phyllanthus: An Ethnopharmacological, Phytochemical, and Pharmacological Review.
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叶下珠属:民族药理学、植物化学和药理学综述

DOI:
10.1155/2016/7584952
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发表时间:
2016
期刊:
Evidence-based complementary and alternative medicine : eCAM
影响因子:
--
通讯作者:
Zhang LZ
Zhang LZ
中科院分区:
其他
文献类型:
--
作者:
Mao X;Wu LF;Guo HL;Chen WJ;Cui YP;Qi Q;Li S;Liang WY;Yang GH;Shao YY;Zhu D;She GM;You Y;Zhang LZ

文献摘要

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叶下珠属(Phyllanthus)植物是大戟科(Euphorbiaceae)叶下珠属(Phyllanthus)植物中的一种,在中国、印度、巴西和东南亚国家长期被用作传统药材。它们可用于治疗消化系统疾病、黄疸和肾结石。本文综述了近几十年来叶下珠属植物的民族药理学、植物化学和药理学研究进展。已分离出510多种化合物,其中大部分为木质素、三萜类、黄酮类和单宁。其显著的抗病毒、抗氧化、抗糖尿病、抗癌等活性已成为研究热点。需要更多的药理筛选和植物化学研究来支持传统用途并开发领先化合物。
The plants of the genus Phyllanthus (Euphorbiaceae) have been used as traditional medicinal materials for a long time in China, India, Brazil, and the Southeast Asian countries. They can be used for the treatment of digestive disease, jaundice, and renal calculus. This review discusses the ethnopharmacological, phytochemical, and pharmacological studies of Phyllanthus over the past few decades. More than 510 compounds have been isolated, the majority of which are lignins, triterpenoids, flavonoids, and tannins. The researches of their remarkable antiviral, antioxidant, antidiabetic, and anticancer activities have become hot topics. More pharmacological screenings and phytochemical investigations are required to support the traditional uses and develop leading compounds.