Value of narrow band imaging in the early diagnosis of laryngeal cancer
Value of narrow band imaging in the early diagnosis of laryngeal cancer
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DOI：
10.1002/hed.23838
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发表时间：
2016-01-01
影响因子：
2.9
通讯作者：
Arens, Christoph
中科院分区：
文献类型：
--
作者：
Kraft, Marcel;Fostiropoulos, Karolos;Arens, Christoph
背景。窄带成像（NBI）是一种用于描述肿瘤特异性新血管生成的新成像技术。本研究的目的是评估NBI在喉癌早期诊断中的价值。方法。这项前瞻性研究包括 205 名连续患有喉部病变并计划进行显微喉镜检查的患者。白光内窥镜检查（WLE）后立即进行NBI，而进行切除活检以进行组织学验证诊断。结果。在识别喉癌及其癌前病变时，NBI联合WLE显示出比单独WLE显着更高的敏感性（97% vs 79%）和准确性（97% vs 90%），但两种方法的特异性（96% vs 95%）基本相同。结论。 NBI 能够快速检测和描绘可疑病变。此外，这种非侵入性方法对于多种良性病变也有益。 (C) 2015 年 Wiley 期刊公司。
Background. Narrow band imaging (NBI) is a new imaging technique for the depiction of tumor-specific neoangiogenesis. The purpose of the present study was to assess the value of NBI in the early diagnosis of laryngeal cancer.Methods. This prospective study includes 205 consecutive patients with a laryngeal lesion scheduled for microlaryngoscopy. NBI was immediately performed after white light endoscopy (WLE), whereas excisional biopsy was carried out for histologic verification of diagnosis.Results. In identifying laryngeal cancer and its precursor lesions, NBI with WLE showed a significantly higher sensitivity (97% vs 79%) and accuracy (97% vs 90%) than WLE alone, but the specificity (96% vs 95%) was essentially equal in both methods.Conclusion. NBI qualifies for rapid detection and delineation of suspicious lesions. Additionally, this noninvasive method is also beneficial in a variety of benign lesions. (C) 2015 Wiley Periodicals, Inc.