Imaging the ocular anterior segment with real-time, full-range Fourier-Domain optical coherence tomography
Imaging the ocular anterior segment with real-time, full-range Fourier-Domain optical coherence tomography
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DOI：
10.1001/archopht.126.4.537
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发表时间：
2008-04-01
影响因子：
--
通讯作者：
Izatt, Joseph A.
中科院分区：
文献类型：
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作者：
Sarunic, Marinko V.;Asrani, Sanjay;Izatt, Joseph A.
我们已经证明了一种新的傅立叶域光学相干断层扫描系统和信号处理算法的全方位，实时，无伪影定量成像的前房。以6.7图像/s的速度采集并显示包含1024 X 800像素（轴向X横向）的横截面全范围图像。在4.5秒内采集包括1024 X 400 X 60像素（轴向X侧向X仰角）的体积数据，并在后处理中进行单个切片的实时可视化和三维重建。观察角膜、利姆布斯、虹膜、前透镜囊、小梁网和Schlemm管的详细情况。从体积数据中获得角膜上皮和内皮的定量表面高度图，并用于生成角膜厚度图。
We have demonstrated a novel Fourier-domain optical coherence tomography system and signal-processing algorithm for full-range, real-time, artifact-free quantitative imaging of the anterior chamber. Cross-sectional full-range images comprising 1024 X 800 pixels (axial X lateral) were acquired and displayed at 6.7 images/s. Volumetric data comprising 1024 X 400 X 60 pixels (axial X lateral X elevation) were acquired in 4.5 seconds with real-time visualization of individual slices and 3-dimensional reconstruction performed in postprocessing. Details of the cornea, limbus, iris, anterior lens capsule, trabecular meshwork, and Schlemm's canal were visualized. Quantitative surface height maps of the corneal epithelium and endothelium were obtained from the volumetric data and used to generate corneal thickness maps.