The epidemiology of dry eye in Melbourne, Australia
The epidemiology of dry eye in Melbourne, Australia
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DOI：
10.1016/s0161-6420(98)96016-x
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发表时间：
1998-06-01
期刊：
影响因子：
13.7
通讯作者：
Taylor, HR
中科院分区：
文献类型：
--
作者：
McCarty, CA;Bansal, AK;Taylor, HR
目的：描述干眼症的流行病学在成人人口的墨尔本，Australia.Design：一个横断面患病率study.Participants：参与者被招募的家庭人口普查从两个9集群的墨尔本视力障碍项目，一个基于人口的研究年龄相关的眼病在40岁及以上的年龄组的墨尔本，澳大利亚。926人（占合格人数的82.3%）参加了研究; 433人（46.8%）为男性。他们的年龄从40岁到97岁不等，平均为59.2岁。主要结果测量：自我报告的症状干眼引起的采访者管理的问卷调查。干眼的四个客观评估：Schirmer试验，泪膜破裂时间，玫瑰红染色，和荧光素角膜染色。对所有参与者进行标准化临床裂隙灯检查。干眼症的个体体征或症状定义为：虎红> 3，Schirmers < 8，泪膜破裂时间< 8，荧光素染色> 1/3，症状严重结果：干眼症的诊断如下：10.8%通过虎红，16.3%通过Schirmer试验，8.6%通过泪膜破裂时间，1.5%通过荧光素染色，7.4%具有两个或更多个体征，5.5%具有任何不归因于花粉热的严重症状。女性更可能报告严重的干眼症状（比值比[OR] = 1.85; 95%置信限[CL] = 1.01，3.41）。两种或两种以上干眼症体征的风险因素包括年龄（OR = 1.04; 95%CL = 1.01，1.06）和自我报告的关节炎（OR = 3.27; 95%CL = 1.74，6.17）。排除21人（2.27%）谁戴隐形眼镜后，这些结果没有改变。结论：这是第一次报告的人口为基础的数据在澳大利亚干眼。干眼症的患病率因体征和症状而异。
Objective: To describe the epidemiology of dry eye in the adult population of Melbourne, Australia.Design: A cross-sectional prevalence study.Participants: Participants were recruited by a household census from two of nine clusters of the Melbourne Visual Impairment Project, a population-based study of age-related eye disease in the 40 and older age group of Melbourne, Australia. Nine hundred and twenty-six (82.3% of eligible) people participated; 433 (46.8%) were male. They ranged in age from 40 to 97 years, with a mean of 59.2 years.Main Outcome Measures: Self-reported symptoms of dry eye were elicited by an interviewer-administered questionnaire. Four objective assessments of dry eye were made: Schirmer's test, tear film breakup time, rose bengal staining, and fluorescein corneal staining. A standardized clinical slit-lamp examination was performed on all participants. Dry eye for the individual signs or symptoms was defined as: rose bengal > 3, Schirmers < 8, tear film breakup time < 8, > 1/3 fluorescein staining, and severe symptoms (3 on a scale of 0 to 3).Results: Dry eye was diagnosed as follows: 10.8% by rose bengal, 16.3% by Schirmer's test, 8.6% by tear film breakup time, 1.5% by fluorescein staining, 7.4% with two or more signs, and 5.5% with any severe symptom not attributed to hay fever. Women were more likely to report severe symptoms of dry eye (odds ratio [OR] = 1.85; 95% confidence limits [CL] = 1.01, 3.41). Risk factors for two or more signs of dry eye include age (OR = 1.04; 95% CL = 1.01, 1.06), and self-report of arthritis (OR = 3.27; 95% CL = 1.74, 6.17). These results were not changed after excluding the 21 people (2.27%) who wore contact lenses.Conclusions: These are the first reported population-based data of dry eye in Australia. The prevalence of dry eye varies by sign and symptom.