Risk of hospital admission with coronavirus disease 2019 in healthcare workers and their households: nationwide linkage cohort study.
Risk of hospital admission with coronavirus disease 2019 in healthcare workers and their households: nationwide linkage cohort study.
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DOI：
10.1136/bmj.m3582
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发表时间：
2020-10-28
期刊：
影响因子：
--
通讯作者：
McAllister DA
中科院分区：
文献类型：
--
作者：
Shah ASV;Wood R;Gribben C;Caldwell D;Bishop J;Weir A;Kennedy S;Reid M;Smith-Palmer A;Goldberg D;McMenamin J;Fischbacher C;Robertson C;Hutchinson S;McKeigue P;Colhoun H;McAllister DA
评估面向患者和非面向患者的医护人员及其家庭成员因2019冠状病毒病（COVID-19）住院的风险。全国连锁队列研究。英国苏格兰，2020年3月1日至6月6日。年龄在18-65岁之间的医疗保健工作者、他们的家庭以及其他普通人群。因新冠肺炎入院。研究对象包括158 445名医护人员，当中大部分（90 733人; 57.3%）为面对病人的医护人员，以及229 905名家庭成员。在工作年龄人群（18-65奥尔兹）中因COVID-19住院的所有患者中，17.2%（360/2097）为医护人员或其家庭。调整年龄、性别、种族、社会经济剥夺和合并症后，非患者面对的医护人员及其家庭因新冠肺炎入院的风险与普通人群相似（风险比分别为0.81（95%置信区间0.52至1.26）和0.86（0.49至1.51））。然而，在调整相同协变量的模型中，与非患者面对的医护人员相比，患者面对的医护人员风险更高（风险比3.30，2.13至5.13），患者面对的医护人员的家庭成员也是如此（1.79，1.10至2.91）。将面向患者的医护人员细分为在“前门”、重症监护和非重症监护气溶胶发生环境和其他环境中工作的医护人员后，前门工作人员的风险较高（风险比2.09，1.49 - 2.94）。对于大多数患者面对的医护人员及其家庭，估计的covid-19住院的绝对风险小于0.5%，但在患有合并症的老年男性中，这一风险为1%及以上。在新冠肺炎住院病例中，有六分之一是医护人员及其家庭。尽管入院的绝对风险总体较低，但患者面对的医护人员及其家庭成员因新冠肺炎入院的风险分别增加了三倍和两倍。
To assess the risk of hospital admission for coronavirus disease 2019 (covid-19) among patient facing and non-patient facing healthcare workers and their household members. Nationwide linkage cohort study. Scotland, UK, 1 March to 6 June 2020. Healthcare workers aged 18-65 years, their households, and other members of the general population. Admission to hospital with covid-19. The cohort comprised 158 445 healthcare workers, most of them (90 733; 57.3%) being patient facing, and 229 905 household members. Of all hospital admissions for covid-19 in the working age population (18-65 year olds), 17.2% (360/2097) were in healthcare workers or their households. After adjustment for age, sex, ethnicity, socioeconomic deprivation, and comorbidity, the risk of admission due to covid-19 in non-patient facing healthcare workers and their households was similar to the risk in the general population (hazard ratio 0.81 (95% confidence interval 0.52 to 1.26) and 0.86 (0.49 to 1.51), respectively). In models adjusting for the same covariates, however, patient facing healthcare workers, compared with non-patient facing healthcare workers, were at higher risk (hazard ratio 3.30, 2.13 to 5.13), as were household members of patient facing healthcare workers (1.79, 1.10 to 2.91). After sub-division of patient facing healthcare workers into those who worked in “front door,” intensive care, and non-intensive care aerosol generating settings and other, those in front door roles were at higher risk (hazard ratio 2.09, 1.49 to 2.94). For most patient facing healthcare workers and their households, the estimated absolute risk of hospital admission with covid-19 was less than 0.5%, but it was 1% and above in older men with comorbidity. Healthcare workers and their households contributed a sixth of covid-19 cases admitted to hospital. Although the absolute risk of admission was low overall, patient facing healthcare workers and their household members had threefold and twofold increased risks of admission with covid-19.
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DOI：
10.1016/s0140-6736(18)31923-8
发表时间：
2018-09-15
期刊：
Lancet (London, England)
影响因子：
--
作者：
Shah ASV;Anand A;Strachan FE;Ferry AV;Lee KK;Chapman AR;Sandeman D;Stables CL;Adamson PD;Andrews JPM;Anwar MS;Hung J;Moss AJ;O'Brien R;Berry C;Findlay I;Walker S;Cruickshank A;Reid A;Gray A;Collinson PO;Apple FS;McAllister DA;Maguire D;Fox KAA;Newby DE;Tuck C;Harkess R;Parker RA;Keerie C;Weir CJ;Mills NL;High-STEACS Investigators
通讯作者：
High-STEACS Investigators
影响因子：
4.1
作者：
McConnell, Doug
通讯作者：
McConnell, Doug
影响因子：
158.5
作者：
McMichael, Temet M.;Currie, Dustin W.;Duchin, Jeffrey S.
通讯作者：
Duchin, Jeffrey S.
影响因子：
37.8
作者：
Shah, Anoop S., V;McAllister, David A.;Cruden, Nicholas L.
通讯作者：
Cruden, Nicholas L.
影响因子：
168.9
作者：
Pollan, Marina;Perez-Gomez, Beatriz;Yotti, Raquel
通讯作者：
Yotti, Raquel