Intact emotion-cognition interaction in schizophrenia patients and first-degree relatives: Evidence from an emotional antisaccade task
Intact emotion-cognition interaction in schizophrenia patients and first-degree relatives: Evidence from an emotional antisaccade task
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DOI：
10.1016/j.bandc.2013.05.007
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发表时间：
2013-08-01
影响因子：
2.5
通讯作者：
Ettinger, Ulrich
中科院分区：
文献类型：
--
作者：
Aichert, Desiree S.;Derntl, Birgit;Ettinger, Ulrich
精神分裂症患者在认知控制和许多情感领域都有缺陷。反扫视任务是一种认知控制的测量，需要抑制反射样眼球运动到外围刺激。已被证明是调制的外围刺激的情绪内容，情绪刺激导致更高的错误率比中性刺激，反映了内隐的情绪处理效果。本研究旨在探讨精神分裂症患者、精神分裂症患者的一级亲属和健康对照者在威胁相关的情绪面部刺激下的反突击表现。15名患者，22名亲属和26名对照，性别，年龄和语言智力相匹配，进行了一项反accade任务，面部图片显示厌恶，恐惧和中性的表情作为外周刺激。我们观察到精神分裂症患者的反跳错误率高于一级亲属和对照组。亲属和对照组之间没有显著差异。反突击错误率的影响的情绪性质的刺激：参与者有较高的反突击错误率相比，中立和厌恶的面孔，在应对恐惧的面孔。由于这种情绪对认知控制的影响在两组之间没有差异，我们得出结论，精神分裂症患者和有患病风险的患者对情绪面孔的内隐处理是完整的。(C)2013 Elsevier Inc. All rights reserved.
Schizophrenia patients have deficits in cognitive control as well as in a number of emotional domains. The antisaccade task is a measure of cognitive control that requires the inhibition of a reflex-like eye movement to a peripheral stimulus. Antisaccade performance has been shown to be modulated by the emotional content of the peripheral stimuli, with emotional stimuli leading to higher error rates than neutral stimuli, reflecting an implicit emotion processing effect. The aim of the present study was to investigate the impact on antisaccade performance of threat-related emotional facial stimuli in schizophrenia patients, first-degree relatives of schizophrenia patients and healthy controls. Fifteen patients, 22 relatives and 26 controls, matched for gender, age and verbal intelligence, carried out an antisaccade task with pictures of faces displaying disgusted, fearful and neutral expressions as peripheral stimuli. We observed higher antisaccade error rates in schizophrenia patients compared to first-degree relatives and controls. Relatives and controls did not differ significantly from each other. Antisaccade error rate was influenced by the emotional nature of the stimuli: participants had higher antisaccade error rates in response to fearful faces compared to neutral and disgusted faces. As this emotional influence on cognitive control did not differ between groups we conclude that implicit processing of emotional faces is intact in patients with schizophrenia and those at risk for the illness. (C) 2013 Elsevier Inc. All rights reserved.