Hierarchical self-assembly of 3D amphiphilic discrete organoplatinum(II) metallacage in water
Hierarchical self-assembly of 3D amphiphilic discrete organoplatinum(II) metallacage in water
复制标题
3D 两亲离散有机铂 (II) 金属笼在水中的分层自组装
DOI：
10.1016/j.cclet.2019.08.036
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发表时间：
2020-03-01
影响因子：
9.1
通讯作者：
Yao, Yong
中科院分区：
文献类型：
--
作者：
Cai, Yan;Wang, Yang;Yao, Yong
在这里，我们描述了一个离散的3D两亲性金属笼4的设计和合成，其中四棱柱形框架作为疏水核和聚（乙二醇）（PEG）链作为亲水尾。化合物4的结构经H-1 NMR、P-31 NMR和电喷雾飞行时间质谱（ESI-TOF-MS）表征。值得注意的是，4与它的长PEG尾巴随后有序成胶束在低浓度（1.20 × 10（-6）mol/L）在水中。随着浓度的增加和培养时间的延长，胶束可以进一步自组装成纳米纤维和纳米带。考虑到配位键的动力学性质，这些结构在外界刺激下表现出可逆的转变。(C)2019中国化学会、中国医学科学院药物研究所。Elsevier B. V.出版，保留所有权利。
Here we described the design and synthesis of a discrete 3D amphiphilic metallacage 4, in which the tetragonal prismatic frameworks act as the hydrophobic cores and the poly(ethylene glycol) (PEG) chains as the hydrophilic tails. The structure of 4 was characterized by H-1 NMR, P-31 NMR and electrospray ionization time-of-flight mass spectrometry (ESI-TOF-MS). Notably, 4 with its long PEG tails was subsequently ordered into micelles at a low concentration (1.20 x 10(-6) mol/L) in water. As the concentration and cultivation time increased, the micelles can further self-assembly into nanofibers and nanoribbons. Considering the dynamic property of the coordination bond, these structures show reversible transformation under external stimuli. (C) 2019 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.