A phenomenological model that predicts forces generated when electrical stimulation is superimposed on submaximal volitional contractions
A phenomenological model that predicts forces generated when electrical stimulation is superimposed on submaximal volitional contractions
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DOI：
10.1152/japplphysiol.01231.2009
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发表时间：
2010-06-01
影响因子：
3.3
通讯作者：
Binder-Macleod, Stuart A.
中科院分区：
文献类型：
--
作者：
Perumal, Ramu;Wexler, Anthony S.;Binder-Macleod, Stuart A.
Perumal R，Wexler AS，Kesar TM，Jancosko A，Laufer Y，Binder-Macleod SA.一个现象学模型，预测当电刺激叠加在次最大意志收缩上时产生的力。J Appl Physiol 108：1595-1604，2010.首次发表于2010年3月18日; doi：10.1152/japplphysiol.01231.2009.-在自主收缩期间叠加电刺激用于在中枢神经系统损伤的个体中产生功能性运动，以评估激活肌肉的能力，表征疲劳的性质，并在术后康复期间改善肌肉力量。目前，自主收缩和电诱发力的总和的方式还没有很好的理解。本研究的目的是开发一个模型，预测电刺激叠加在意志收缩时获得的力。对12名健康受试者的股四头肌进行了测试。我们的研究结果表明，在意志收缩过程中叠加电刺激时产生的总力可以用方程T = V + S[（MaxForce-V）/MaxForce]（N），其中T是产生的总力，V是单独响应于意志收缩的力，S是单独响应于电刺激的力，MaxForce是肌肉的最大力产生能力，N是一个参数，我们认为它取决于运动单位募集顺序和自发收缩与电诱发收缩之间的放电率的差异。此外，我们的研究结果表明，该模型准确地预测（组内相关系数>= 0.97）的总力响应于一个广泛的刺激强度和频率叠加在一个广泛的意志收缩水平。因此，该模型将有助于临床医生和科学家预测在部分瘫痪的个体中产生目标力水平所需的刺激量。
Perumal R, Wexler AS, Kesar TM, Jancosko A, Laufer Y, Binder-Macleod SA. A phenomenological model that predicts forces generated when electrical stimulation is superimposed on submaximal volitional contractions. J Appl Physiol 108: 1595-1604, 2010. First published March 18, 2010; doi:10.1152/japplphysiol.01231.2009.-Superimposition of electrical stimulation during voluntary contractions is used to produce functional movements in individuals with central nervous system impairment, to evaluate the ability to activate a muscle, to characterize the nature of fatigue, and to improve muscle strength during postsurgical rehabilitation. Currently, the manner in which voluntary contractions and electrically elicited forces summate is not well understood. The objective of the present study is to develop a model that predicts the forces obtained when electrical stimulation is superimposed on a volitional contraction. Quadriceps femoris muscles of 12 able-bodied subjects were tested. Our results showed that the total force produced when electrical stimulation was superimposed during a volitional contraction could be modeled by the equation T = V + S[(MaxForce - V)/MaxForce](N), where T is the total force produced, V is the force in response to volitional contraction alone, S is the force response to the electrical stimulation alone, MaxForce is the maximum force-generating ability of the muscle, and N is a parameter that we posit depends on the differences in the motor unit recruitment order and firing rates between volitional and electrically elicited contractions. In addition, our results showed that the model predicted accurately (intraclass correlation coefficient >= 0.97) the total force in response to a wide range of stimulation intensities and frequencies superimposed on a wide range of volitional contraction levels. Thus the model will be helpful to clinicians and scientists to predict the amount of stimulation needed to produce the targeted force levels in individuals with partial paralysis.