Accuracy of the Edinburgh Postnatal Depression Scale (EPDS) for screening to detect major depression among pregnant and postpartum women: systematic review and meta-analysis of individual participant data.
Accuracy of the Edinburgh Postnatal Depression Scale (EPDS) for screening to detect major depression among pregnant and postpartum women: systematic review and meta-analysis of individual participant data.
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DOI：
10.1136/bmj.m4022
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发表时间：
2020-11-11
期刊：
影响因子：
--
通讯作者：
DEPRESsion Screening Data (DEPRESSD) EPDS Group
中科院分区：
文献类型：
--
作者：
Levis B;Negeri Z;Sun Y;Benedetti A;Thombs BD;DEPRESsion Screening Data (DEPRESSD) EPDS Group
评价爱丁堡产后抑郁量表（EPDS）用于筛查孕妇和产后妇女抑郁症的价值。个体参与者数据荟萃分析。Medline，Medline过程中和其他非索引引文，PsycINFO和Web of Science（从成立到2018年10月3日）。符合条件的数据集包括EPDS评分和基于有效诊断访谈的重度抑郁症分类。双变量随机效应荟萃分析被用来估计EPDS的敏感性和特异性相比，半结构化，完全结构化（迷你国际神经精神访谈（MINI）排除），和MINI诊断访谈分别使用个人参与者的数据。一阶段荟萃回归被用来检查参考标准类别和参与者的特征的准确性。个体参与者数据来自83项合格研究中的58项（70%; 22788名合格参与者中的15557名（68%），2069名患有重度抑郁症）。在参比标准品中，当临界值为11或更高时，组合灵敏度和特异性最大化。在半结构化访谈的研究中，（36个研究，9066名参与者，1330名重性抑郁症患者），敏感性和特异性分别为0.85（95%置信区间0.79 - 0.90）和0.84（0.79至0.88）对于10或更高的临界值，0.81对于截止值11或更高，分别为0.66（0.75至0.87）和0.88（0.85至0.91），对于截止值13或更高，分别为0.66（0.58至0.74）和0.95（0.92至0.96）。参考标准品和亚组之间的准确度相似，包括孕妇和产后妇女。EPDS临界值为11或更高时，敏感性和特异性最大化;临界值为13或更高时，敏感性较低，但特异性更高。为了识别具有较高症状水平的孕妇和产后妇女，可以使用13或更高的截止值。如果目的是避免假阴性并识别符合诊断标准的大多数患者，则可以使用较低的截止值。PROSPERO（CRD 42015024785）。
To evaluate the Edinburgh Postnatal Depression Scale (EPDS) for screening to detect major depression in pregnant and postpartum women. Individual participant data meta-analysis. Medline, Medline In-Process and Other Non-Indexed Citations, PsycINFO, and Web of Science (from inception to 3 October 2018). Eligible datasets included EPDS scores and major depression classification based on validated diagnostic interviews. Bivariate random effects meta-analysis was used to estimate EPDS sensitivity and specificity compared with semi-structured, fully structured (Mini International Neuropsychiatric Interview (MINI) excluded), and MINI diagnostic interviews separately using individual participant data. One stage meta-regression was used to examine accuracy by reference standard categories and participant characteristics. Individual participant data were obtained from 58 of 83 eligible studies (70%; 15 557 of 22 788 eligible participants (68%), 2069 with major depression). Combined sensitivity and specificity was maximised at a cut-off value of 11 or higher across reference standards. Among studies with a semi-structured interview (36 studies, 9066 participants, 1330 with major depression), sensitivity and specificity were 0.85 (95% confidence interval 0.79 to 0.90) and 0.84 (0.79 to 0.88) for a cut-off value of 10 or higher, 0.81 (0.75 to 0.87) and 0.88 (0.85 to 0.91) for a cut-off value of 11 or higher, and 0.66 (0.58 to 0.74) and 0.95 (0.92 to 0.96) for a cut-off value of 13 or higher, respectively. Accuracy was similar across reference standards and subgroups, including for pregnant and postpartum women. An EPDS cut-off value of 11 or higher maximised combined sensitivity and specificity; a cut-off value of 13 or higher was less sensitive but more specific. To identify pregnant and postpartum women with higher symptom levels, a cut-off of 13 or higher could be used. Lower cut-off values could be used if the intention is to avoid false negatives and identify most patients who meet diagnostic criteria. PROSPERO (CRD42015024785).
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影响因子：
2
作者：
Riley, Richard D.;Dodd, Susanna R.;Williamson, Paula R.
通讯作者：
Williamson, Paula R.
DOI：
10.1177/070674370505001308
发表时间：
2005-11-01
影响因子：
4
作者：
Kurdyak, PA;Gnam, WH
通讯作者：
Gnam, WH
DOI：
10.1192/bjp.2018.54
发表时间：
2018-06
期刊：
The British journal of psychiatry : the journal of mental science
影响因子：
--
作者：
Levis B;Benedetti A;Riehm KE;Saadat N;Levis AW;Azar M;Rice DB;Chiovitti MJ;Sanchez TA;Cuijpers P;Gilbody S;Ioannidis JPA;Kloda LA;McMillan D;Patten SB;Shrier I;Steele RJ;Ziegelstein RC;Akena DH;Arroll B;Ayalon L;Baradaran HR;Baron M;Beraldi A;Bombardier CH;Butterworth P;Carter G;Chagas MH;Chan JCN;Cholera R;Chowdhary N;Clover K;Conwell Y;de Man-van Ginkel JM;Delgadillo J;Fann JR;Fischer FH;Fischler B;Fung D;Gelaye B;Goodyear-Smith F;Greeno CG;Hall BJ;Hambridge J;Harrison PA;Hegerl U;Hides L;Hobfoll SE;Hudson M;Hyphantis T;Inagaki M;Ismail K;Jetté N;Khamseh ME;Kiely KM;Lamers F;Liu SI;Lotrakul M;Loureiro SR;Löwe B;Marsh L;McGuire A;Mohd Sidik S;Munhoz TN;Muramatsu K;Osório FL;Patel V;Pence BW;Persoons P;Picardi A;Rooney AG;Santos IS;Shaaban J;Sidebottom A;Simning A;Stafford L;Sung S;Tan PLL;Turner A;van der Feltz-Cornelis CM;van Weert HC;Vöhringer PA;White J;Whooley MA;Winkley K;Yamada M;Zhang Y;Thombs BD
通讯作者：
Thombs BD
影响因子：
2
作者：
Higgins, JPT;Thompson, SG
通讯作者：
Thompson, SG
影响因子：
7.8
作者：
Lecrubier, Y;Sheehan, DV;Dunbar, GC
通讯作者：
Dunbar, GC