Comprehensive Analysis of Volatile Compounds in Mouthpiece Cigarette Adhesive by Coupling Headspace with Gas Chromatography–Mass Spectrometry
Comprehensive Analysis of Volatile Compounds in Mouthpiece Cigarette Adhesive by Coupling Headspace with Gas Chromatography–Mass Spectrometry
复制标题
通过顶空与气相色谱-质谱联用对烟嘴粘合剂中的挥发性化合物进行综合分析。
DOI：
10.1093/jaoacint/qsaa160
复制
发表时间：
2020
影响因子：
1.6
通讯作者：
Feng Yu-Qi
中科院分区：
文献类型：
--
作者：
Wei Min;Zheng Feng;Song Xuyan;Li Ran;Pan Xi;Guo Guoning;Yu Qiong-Wei;Feng Yu-Qi
背景：吸嘴香烟粘合剂中的一些挥发性化合物会散发刺激性气味，影响吸烟的味道。目的：建立一种快速、简便的口罩烟用胶粘剂中挥发性化合物的分析方法。方法：采用顶空气相色谱(HS)进样与GC-MS联用进行定性和定量。通过比较被检测挥发性化合物与相应标样的保留时间和质谱图，进一步鉴定出与波谱库相似度大于85%的被检测化合物。结果：准确鉴定了口罩烟用胶粘剂中的11种挥发性化合物。定量分析方法的线性范围为20~147.7 ng/g，日内、日间相对标准偏差均小于19.8%。该方法的回收率为68.1%~108.3%。结论：该方法快速、简便、准确，可用于口罩香烟胶粘剂中挥发性化合物的定性和定量分析。
Background: Some volatile compounds in mouthpiece cigarette adhesive emit irritating odors and affect the taste of smoking.cigarettes. Therefore, it is necessary to monitor the volatile compounds in mouthpiece cigarette adhesive..Objectives: A rapid and simple analytical method of volatile compounds in mouthpiece cigarette adhesive was established..Methods: In this study, headspace (HS) injection coupled with GC–MS was utilized for qualitative and quantitative analysis..Initially, the volatile compounds in mouthpiece cigarette adhesives were detected by HS-GC–MS, followed by spectrum.library retrieval. The detected compounds with the similarity to a spectrum library of more than 85% were further identified.by comparing the retention time and mass spectra of the detected volatile compounds and those of the corresponding.standard samples. The quantitative analysis of nine identified volatile compounds was performed..Results: Eleven volatile compounds in the mouthpiece cigarette adhesive were accurately identified. The quantitative.analytical method of nine volatile compounds in mouthpiece cigarette adhesive was validated to have good linearities (R2 >.0.9932) within the range of 20–5000 ng/g. The detection limits of 9 compounds were within the range of 3.1–147.7 ng/g..The intra- and inter-day relative standard deviations were less than 19.8%. The recoveries of these 9 compounds spiked into.mouthpiece cigarette adhesive were 68.1–108.3%..Conclusions: The proposed method is rapid, simple, and accurate for qualitative and quantitative analysis of volatile.compounds in the mouthpiece cigarette adhesive..Highlights: The developed analytical method is expected to be used to monitor volatile compounds in various adhesives.