Reliability and validity of the SF-36 Health Survey Questionnaire in patients with brain tumors: a cross-sectional study.
Reliability and validity of the SF-36 Health Survey Questionnaire in patients with brain tumors: a cross-sectional study.
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DOI：
10.1186/s12955-017-0665-1
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发表时间：
2017-05-04
影响因子：
3.6
通讯作者：
Bunevicius A
中科院分区：
文献类型：
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作者：
Bunevicius A
健康相关生活质量（HRQoL）的恶化在脑肿瘤患者中很常见。本研究评估了医学结局研究36-Item Short Form （SF-36）在脑肿瘤患者中的效度和可靠性。对277例脑肿瘤手术患者进行HRQoL （SF-36问卷）评估；抑郁症状（贝克抑郁量表- ii或BDI-II）；功能状态（Barthel指数或BI）。最终的组织学诊断来自病理报告。227例（完成率82%）患者（69%为女性，平均年龄55.8±14.4岁）完成了SF-36问卷。最常见的脑肿瘤诊断是脑膜瘤（40%），其次是高度胶质瘤（19%）。数据缺失率≤4%。内部一致性足够（Cronbach α≥）。728)，但社会功能(Cronbach α =。527)和一般健康(Cronbach α =。693)分量表。角色限制子量表的最高（≥36%）和最低（≥22%）有效率最高。身体健康的SF-36量表与BI得分的相关性最强，而情绪健康的SF-36量表与BDI-II得分的相关性最强。轻度-中度抑郁症状患者（BDI-II评分≥20）在所有SF-36亚量表中得分较低，残疾患者（BI评分<90）在除心理健康外的所有亚量表中得分较低。SF-36在脑肿瘤患者中是一种有效可靠的仪器，因此可以可靠地应用于神经肿瘤学环境中HRQoL的评估。进一步研究SF-36在脑肿瘤患者疾病进展阶段的其他心理测量特性是必要的。
Deterioration of health related quality of life (HRQoL) is common in brain tumor patients. This study evaluated validity and reliability of the Medical Outcomes Study 36-Item Short Form (SF-36) in patients with brain tumors. Two hundred and seventy-seven patients admitted for brain tumor surgery were evaluated for HRQoL (SF-36 questionnaire); depressive symptoms (Beck Depression Inventory-II or BDI-II); and functional status (Barthel index or BI). Final histological diagnosis was obtained from pathology reports. Two-hundred and twenty-seven (completion rate of 82%) patients (69% women; mean age 55.8 ± 14.4 years) completed the SF-36 questionnaire. The most common brain tumor diagnosis was meningioma (40%), followed high-grade glioma (19%). Missing data rates were ≤4%. Internal consistency was adequate for all (Cronbach α ≥ .728) but Social Functioning (Cronbach α = .527) and General Health (Cronbach α = .693) subscales. Ceiling (≥36%) and floor (≥22%) effect rates were the greatest for the Role Limitations subscales. The SF-36 subscales pertaining physical health correlated the strongest with the BI score, while the SF-36 subscales pertaining emotional health correlated the strongest with the BDI-II score. Patients with mild-moderate depressive symptoms (BDI-II score ≥20) scored lower across all SF-36 subscales, and handicap patients (BI score <90) scored the lower across all, but Mental Health, subscales. The SF-36 is a valid and reliable instrument in brain tumor patients and therefore can be reliably applied for evaluation of HRQoL in neuro-oncology setting. Further studies exploring other psychometric properties of the SF-36 in brain tumor patients across disease progression stages are warranted.