Specific effects of polyunsaturated fatty acids on gene expression.
Specific effects of polyunsaturated fatty acids on gene expression.
复制标题
多不饱和脂肪酸对基因表达的具体影响。
DOI：
10.1097/00041433-199602000-00012
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发表时间：
1996
影响因子：
4.4
通讯作者：
Clarke,SD
中科院分区：
文献类型：
--
作者：
Baillie,RA;Jump,DB;Clarke,SD
饮食中的多不饱和脂肪酸调节许多蛋白质的转录，包括几种肝脏脂肪生成酶。一些证据表明，多不饱和脂肪酸并不通过过氧化体增殖物激活的受体来调节肝脏脂肪生成基因的转录，但其机制可能涉及与碳水化合物反应区相关的转录因子。
Dietary polyunsaturated fatty acids modulate the transcription of numerous proteins including several hepatic lipogenic enzymes. Several lines of evidence indicate that polyunsaturated fatty acids do not regulate the transcription of hepatic lipogenic genes via a peroxisomal proliferator-activated receptor, but the mechanism may involve transcription factors related to the carbohydrate response region.