Prevalence and impact of bilateral vestibular hypofunction: results from the 2008 US National Health Interview Survey.
Prevalence and impact of bilateral vestibular hypofunction: results from the 2008 US National Health Interview Survey.
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DOI：
10.1001/jamaoto.2013.3913
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发表时间：
2013-08-01
期刊：
影响因子：
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通讯作者：
Della Santina CC
中科院分区：
文献类型：
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作者：
Ward BK;Agrawal Y;Hoffman HJ;Carey JP;Della Santina CC
严重的双侧前庭功能减退（BVH）可导致失能性视觉障碍、慢性平衡失调和姿势不稳定。我们的目的是评估BVH在美国成年人群中的患病率和功能影响。全国横断面调查及推论验证研究。国家数据库2008年美国国家健康访谈调查（NHIS）平衡和头晕补充的成人参与者（n= 21，782）。基于调查的BVH诊断，所有以下情况：存在头部运动导致的视物模糊、不稳定、在黑暗/不稳定表面和直线路径中行走困难、症状至少为“大问题”并存在至少1年，不存在影响视力的其他神经系统疾病或眼部病理。BVH的患病率、BVH的社会经济和生活质量影响以及跌倒风险。这项调查调整后的全国估计表明，2008年BVH的患病率为28/100，000美国成年人（64，046名美国人）。44%的BVH参与者报告由于症状而改变了他们的驾驶习惯，56%的人报告减少了社交活动，58%的人报告日常生活活动困难。与所有受访者相比，BVH受访者在多变量分析中跌倒的几率增加了31倍，其中25%的人报告了最近的跌倒相关伤害。根据一项全国代表性调查中特定症状的存在情况估计，BVH对社会经济和生活质量具有相当大的影响，并显著增加了跌倒风险。这些数据支持需要新的治疗策略BVH，包括前庭康复和植入式前庭假体。
Profound bilateral vestibular hypofunction (BVH) causes disabling oscillopsia, chronic disequilibrium and postural instability. Our aim was to assess prevalence and functional impact of BVH in the U.S. adult population. National cross-sectional survey and corollary validation study. National database Adult participants in the 2008 Balance and Dizziness Supplement to the United States National Health Interview Survey (NHIS), (n=21,782). Survey-based diagnosis of BVH, all of the following: presence of visual blurring with head movement, unsteadiness, difficulty walking in darkness/unsteady surfaces and in a straight path, symptoms being at least “a big problem” and present for at least 1 year, in the absence of other neurologic conditions or eye pathology affecting vision. Prevalence of BVH, socioeconomic and quality-of-life impact of BVH, and fall risk. Adjusted national estimates from this survey indicate the prevalence of BVH in 2008 was 28/100,000 U.S. adults (64,046 Americans). 44% of participants with BVH reported changing their driving habits because of their symptoms, 56% reported reduced participation in social activities, and 58% reported difficulties with activities of daily living. Respondents with BVH had a 31-fold increase in the odds of falling in multivariate analyses compared to all respondents, with 25% reporting a recent fall-related injury. BVH, as estimated by the presence of specific symptoms in a nationally representative survey, has considerable socioeconomic and quality-of-life impacts and significantly increases fall risk. These data support the need for new therapeutic strategies for BVH, including vestibular rehabilitation and implantable vestibular prostheses.