Critical Shell Thickness of Core/Shell Upconversion Luminescence Nanoplatform for FRET Application
Critical Shell Thickness of Core/Shell Upconversion Luminescence Nanoplatform for FRET Application
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用于FRET应用的核/壳上转换发光纳米平台的临界壳厚度
DOI：
10.1021/jz200922f
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发表时间：
2011-09-01
影响因子：
5.7
通讯作者：
Zhang, Hong
中科院分区：
文献类型：
--
作者：
Wang, Yu;Liu, Kai;Zhang, Hong
几乎所有用于福斯特共振能量转移（FRET）应用的发光上转换纳米颗粒都是裸核，这是基于能量转移效率被优化的考虑，因为能量供体和受体之间的距离被最小化。另一方面，核/壳结构在最小化发光供体的激发能的非辐射损失方面是有效的。在这项工作中，我们使用核/壳上转换NaYF 4：Yb 3+，Er 3 +@NaYF4纳米粒子和玫瑰红光敏剂构建FRET缀合物。从电子物理学和单线态氧的产生，我们已经确定，核/壳结构的纳米粒子比裸核的FRET应用。更重要的是，我们发现，存在一个临界壳层厚度的最佳FRET性能。在我们建立的模型中，临界壳层厚度是上转换和FRET效率的相对最佳条件之间的权衡。这项工作将导致更有效的基于FRET的纳米材料应用。
Almost all the luminescence upconversion nanoparticles used for Forster resonant energy transfer (FRET) applications are bare cores based on the consideration that the energy transfer efficiency is optimized because the distance between energy donors and acceptors is minimized. On the other hand, it is well proved that core/shell structure is efficient in minimizing the nonradiative loss of excitation energy of the luminescence donors. In this work we use core/shell upconversion NaYF4:Yb3+,Er3+@NaYF4 nanoparticles and rose bengal photosensitizer to construct a FRET conjugate. From the photophysics and singlet oxygen generation we have determined that the core/shell structured nanoparticles are better than bare cores for FRET applications. More importantly, we have found that there exists a critical shell thickness for the best FRET performance. In the model we have established, the critical shell thickness is a trade-off between the opposing optimal conditions for upconversion and FRET efficiency. This work shall lead to more efficient FRET-based applications of nanomaterials.