SINGLE COURSE VERSUS MAINTENANCE BACILLUS CALMETTE-GUERIN THERAPY FOR SUPERFICIAL BLADDER-TUMORS - A PROSPECTIVE, RANDOMIZED TRIAL
SINGLE COURSE VERSUS MAINTENANCE BACILLUS CALMETTE-GUERIN THERAPY FOR SUPERFICIAL BLADDER-TUMORS - A PROSPECTIVE, RANDOMIZED TRIAL
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DOI：
10.1016/s0022-5347(17)43125-9
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发表时间：
1987-08-01
影响因子：
6.6
通讯作者：
CATALONA, WJ
中科院分区：
文献类型：
--
作者：
HUDSON, MA;RATLIFF, TL;CATALONA, WJ
共有42例复发性浅表性膀胱肿瘤或原位癌患者进入了一项前瞻性随机试验，以比较卡介苗治疗与卡介苗季度维持滴注的疗效。维持治疗并没有降低对初始疗程有反应的患者的进一步膀胱肿瘤复发率或复发间隔。然而，观察到维持卡介苗治疗的毒性延长。
A total of 42 patients with recurrent superficial bladder tumors or carcinoma in situ entered a prospective, randomized trial to compare the efficacy of bacillus Calmette-Guerin therapy with and without quarterly maintenance instillations of bacillus Calmette-Guerin. Maintenance therapy did not reduce further bladder tumor recurrence rates or the interval to recurrence in patients who responded to the initial course of therapy. However, prolongation of toxicity was observed with maintenance bacillus Calmette-Guerin therapy.