Some physical factors affecting the acceptance of synthetic materials as tissue implants.
Some physical factors affecting the acceptance of synthetic materials as tissue implants.
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DOI：
10.1111/j.1749-6632.1968.tb20278.x
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发表时间：
1968-01-01
影响因子：
5.2
通讯作者：
Palmer, T E
中科院分区：
文献类型：
--
作者：
Davila, J C;Lautsch, E V;Palmer, T E
Davila et NL.：作为组织植入物的合成材料139和金属中的维生素合金。如果初步结果成立，可以添加碳-石墨和某些陶瓷。*然而，无论所用材料的可接受性如何，假体植入物的设计必须考虑到下列因素。我们已经研究了前面提到的大多数塑料，如固体、海绵和针织或机织织物，包括天鹅绒，以及毛毡形式。我们还研究了多孔金属结构，最近还研究了一些碳毡和陶瓷毡。毛毡，由上述任何一种塑料制成，似乎为种植结构提供了最好的模型。事实上，这是一个人造基质。植入物的孔隙率在粘接过程中是可以控制的。单丝纤维的直径可以优化。假体的机械性能可以通过使用适当的纤维(如短、长、硬、柔软、弹性等)在一定程度上确定。这里提出的原则是基于小牛的研究结果，植入的心脏瓣膜由不同的材料制成，并根据不同的设计。此外，在狗身上，还研究了多种材料的测试植入物，包括心脏和血管壁补片、动脉和静脉节段以及皮下阻滞剂。这些原则中的某些原则以前已经提到过。3-9
Davila et nl.: Synthetics as Tissue Implants 139 and the Vitallium alloys among the metals. Carbon-graphite and certain ceramics may be added if preliminary results hold up.* However, regardless of the ac-ceptability of the materials used, a prosthetic implant must be designed so that the factors enumerated below are taken into account. We have studied most of the plastics noted before as solids, sponges and knitted or woven fabrics, including velour, as well as in felt form. We have also studied porous metal structures and recently some carbon and ceramic felts. Felt, made of any of the above plastics, appears to provide the best model for implant structures. Indeed, it is an artificial stroma. The porosity of the implant can be controlled in the felting process. The caliber of the monofilament fibers can be optimized. Mechanical properties of the prosthesis can be determined to some extent by use of appropriate fibers (ie, short, long, stiff, pliable, elastic, etc.) with or without a binder.The principles proposed here are based on the results of studies, in calves, of implanted cardiac valve prostheses made of various materials and according to diverse designs. In addition, in dogs, test implants of numerous materials including cardiac and vascular wall patches, artery and vein segments and subcutaneous block hplants were studied. Certain of these principles have been alluded to before. 3-9