Funding of US Biomedical Research, 2003-2008

Funding of US Biomedical Research, 2003-2008
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DOI:
10.1001/jama.2009.1987
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发表时间:
2010-01-13
影响因子:
120.7
通讯作者:
Moses, Hamilton, III
Moses, Hamilton, III
中科院分区:
医学1区
文献类型:
--
作者:
Dorsey, E. Ray;de Roulet, Jason;Moses, Hamilton, III

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除了《美国复苏和再投资法案》之外,美国对生物医学研究的资金支持在十年翻了一番之后已经放缓。然而,减缓的程度和范围在很大程度上是unknowed.Objective量化资助的生物医学研究在美国从2003年到2008.Design公开可用的数据被用来量化资助从政府(联邦,州和地方),私人和行业来源。使用回归模型比较了1994-2003年和2003-2007年的财务趋势。美国食品和药物管理局在同一时期批准的新药和器械的数量也evaluated.Main结果测量资金和增长率的来源;美国食品和药物管理局approvals.Results生物医学研究经费从2003年的755亿美元增加到2007年的1011亿美元。2008年,来自美国国立卫生研究院和工业界的资金总额为888亿美元。2007年,经通货膨胀调整后,来自这些来源的资金为902亿美元。经通货膨胀调整后,2003年至2007年的供资增加了14%,复合年增长率为3.4%。相比之下,从1994年到2003年,资金以每年7.8%的速度增长(P
Context With the exception of the American Recovery and Reinvestment Act, funding support for biomedical research in the United States has slowed after a decade of doubling. However, the extent and scope of slowing are largely unknown.Objective To quantify funding of biomedical research in the United States from 2003 to 2008.Design Publicly available data were used to quantify funding from government (federal, state, and local), private, and industry sources. Regression models were used to compare financial trends between 1994-2003 and 2003-2007. The numbers of new drug and device approvals by the US Food and Drug Administration over the same period were also evaluated.Main Outcome Measures Funding and growth rates by source; numbers of US Food and Drug Administration approvals.Results Biomedical research funding increased from $75.5 billion in 2003 to $101.1 billion in 2007. In 2008, funding from the National Institutes of Health and industry totaled $88.8 billion. In 2007, funding from these sources, adjusted for inflation, was $90.2 billion. Adjusted for inflation, funding from 2003 to 2007 increased by 14%, for a compound annual growth rate of 3.4%. By comparison, funding from 1994 to 2003 increased at an annual rate of 7.8% (P