Characteristics of Crimean-Congo hemorrhagic fever virus (Xinjiang strain) in China.
Characteristics of Crimean-Congo hemorrhagic fever virus (Xinjiang strain) in China.
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中国克里米亚-刚果出血热病毒（新疆株）的特征。
DOI：
10.4269/ajtmh.1985.34.1179
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Lee Ling
中科院分区：
文献类型：
--
作者：
Yen Yu;Bao;Yu;Shou;Li Feng;Lingna Kong;Lee Ling
1968年新疆南部出血热暴发流行期间，从亚洲璃眼蜱和绵羊中分离到的病毒株，经补体结合试验和用患者恢复期血清及C-CHF参考抗体进行间接免疫荧光试验，发现与C-CHF病毒相同或密切相关。用乙醚和酸灭活病毒。5-碘脱氧尿苷不抑制病毒合成，表明含有RNA的基因组。在蔗糖中的浮力密度为1.16-1.18 g/cm 3。颗粒重量估计为3.26 +/- 0.46 X 10（8）。病毒颗粒直径为85-105 nm。
Virus strains isolated from blood of patients during a hemorrhagic fever outbreak in 1968 in southern Xinjiang, China, from Hyalomma asiaticum and from sheep, were found to be identical or closely related to Crimean-Congo hemorrhagic fever (C-CHF) virus by complement fixation and indirect immunofluorescence tests with convalescent sera of patients and with C-CHF reference antibody. The virus was inactivated by ether and acid. Viral synthesis was not suppressed by 5-iododeoxyuridine suggesting an RNA-containing genome. The buoyant density in sucrose was 1.16-1.18 g/cm3. The particle weight was estimated at 3.26 +/- 0.46 X 10(8). The diameter of the virus particles was 85-105 nm.